Efficacy of Periodontal Treatment on Glycaemic Control in Diabetic Patients

NCT ID: NCT02563457

Last Updated: 2025-12-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

91 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-02-28

Study Completion Date

2015-08-31

Brief Summary

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This study will assess the efficacy of periodontal treatment in diabetic patient. Patients will be randomized in the periodontal group or in the control group. The control group will received a periodontal treatment after the study.

Detailed Description

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Conditions

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Diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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case

diabetic patients who will receive periodontal treatment blood sampling

Group Type EXPERIMENTAL

periodontal manual treatment

Intervention Type OTHER

periodontal manual treatment

control

diabetic patients without periodontal treatment (no periodontal treatment) blood sampling

Group Type EXPERIMENTAL

no periodontal manual treatment

Intervention Type OTHER

blood sampling

Interventions

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periodontal manual treatment

periodontal manual treatment

Intervention Type OTHER

no periodontal manual treatment

blood sampling

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patient suffering from a periodontitis
* patient with : 7,0% \< Hemoglobin A1c \< 9,5%

Exclusion Criteria

* If an hospitalization is planned within the next 4 months
* Patient suffering from chronic infectious pathology (HIV, hepatitis C virus, hepatitis B virus, mononucleosis)
* Renal insufficiency
* Contra indication for amoxicilline or clindamycin
* Antithrombotic treatment
* Liver disease
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Toulouse

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michel Sixou, MD

Role: PRINCIPAL_INVESTIGATOR

UH Toulouse

Locations

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UH Bordeaux

Bordeaux, , France

Site Status

UHToulouse

Toulouse, , France

Site Status

Countries

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France

References

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Vergnes JN, Canceill T, Vinel A, Laurencin-Dalicieux S, Maupas-Schwalm F, Blasco-Baque V, Hanaire H, Arrive E, Rigalleau V, Nabet C, Sixou M, Gourdy P, Monsarrat P; DIAPERIO Group. The effects of periodontal treatment on diabetic patients: The DIAPERIO randomized controlled trial. J Clin Periodontol. 2018 Oct;45(10):1150-1163. doi: 10.1111/jcpe.13003. Epub 2018 Sep 14.

Reference Type RESULT
PMID: 30136741 (View on PubMed)

Vergnes JN, Arrive E, Gourdy P, Hanaire H, Rigalleau V, Gin H, Sedarat C, Dorignac G, Bou C, Sixou M, Nabet C. Periodontal treatment to improve glycaemic control in diabetic patients: study protocol of the randomized, controlled DIAPERIO trial. Trials. 2009 Aug 2;10:65. doi: 10.1186/1745-6215-10-65.

Reference Type RESULT
PMID: 19646281 (View on PubMed)

Other Identifiers

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08 031 08

Identifier Type: -

Identifier Source: org_study_id

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