Aetiology of Children With Bronchiectasis in China

NCT ID: NCT02555865

Last Updated: 2017-01-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-06-30

Study Completion Date

2022-03-31

Brief Summary

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This multicenter retrospective observation study is designed to investigate the etiology of children with bronchiectasis by review the medical records.

Detailed Description

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This study is divided into two parts. Part I. Retrospective review the 10 years medical records of the children with bronchiectasis from every center, and investigate the etiology of the cases by the standard diagnostic process. Part II. All new cases of bronchiectasis which was confirmed diagnosed at every center from the beginning of the study are made the investigation of the etiology by the standard diagnostic process.

Conditions

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Bronchiectasis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* Internal bronchial diameter greater than the accompanying pulmonary artery.
* lack of bronchial tapering
* bronchi visible in the peripheral 1cm of lung
* bronchial diameter greater than adjacent segmental bronchi

Exclusion Criteria

* It is unable to provide complete medical records or the current condition can not accept the diagnosis process
* It does not agree to participate in the test
Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wuhan women and children's health care center

UNKNOWN

Sponsor Role collaborator

Children's Hospital of Chongqing Medical University

OTHER

Sponsor Role collaborator

Yuying Children's Hospital of Wenzhou Medical University

OTHER

Sponsor Role collaborator

Changchun Children's Hospital

OTHER

Sponsor Role collaborator

Shenzhen Children's Hospital

OTHER_GOV

Sponsor Role collaborator

Jiangxi Province Children's Hospital

OTHER

Sponsor Role collaborator

Shanghai Children's Medical Center

OTHER

Sponsor Role collaborator

First Affiliated Hospital of Guangxi Medical University

OTHER

Sponsor Role collaborator

Tianjin Children's Hospital

OTHER

Sponsor Role collaborator

The First Affiliated Hospital of Xiamen University

OTHER

Sponsor Role collaborator

The Affiliated Hospital Of Guizhou Medical University

OTHER

Sponsor Role collaborator

Shanxi Provincial Maternity and Children's Hospital

OTHER

Sponsor Role collaborator

Beijing Children's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Baoping XU

Chief of Respiratory Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kunling Shen, MD,PhD

Role: STUDY_DIRECTOR

Beijing Children's Hospital of Capital Medical University, China

Baoping Xu, MD,PhD

Role: PRINCIPAL_INVESTIGATOR

Beijing Children's Hospital of Capital Medical University, China

Xiaoxia Peng, MD,PhD

Role: PRINCIPAL_INVESTIGATOR

Beijing Children's Hospital of Capital Medical University, China

Locations

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Beijing Children'S Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Baoping Xu, MD,PhD

Role: CONTACT

861059616308

Facility Contacts

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baoping xu

Role: primary

References

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Barker AF. Bronchiectasis. N Engl J Med. 2002 May 2;346(18):1383-93. doi: 10.1056/NEJMra012519. No abstract available.

Reference Type BACKGROUND
PMID: 11986413 (View on PubMed)

Amorim A, Gracia Roldan J. Bronchiectasis: do we need aetiological investigation? Rev Port Pneumol. 2011 Jan-Feb;17(1):32-40. English, Portuguese.

Reference Type BACKGROUND
PMID: 21251482 (View on PubMed)

Gaillard EA, Carty H, Heaf D, Smyth RL. Reversible bronchial dilatation in children: comparison of serial high-resolution computer tomography scans of the lungs. Eur J Radiol. 2003 Sep;47(3):215-20. doi: 10.1016/s0720-048x(02)00122-5.

Reference Type BACKGROUND
PMID: 12927665 (View on PubMed)

Eastham KM, Fall AJ, Mitchell L, Spencer DA. The need to redefine non-cystic fibrosis bronchiectasis in childhood. Thorax. 2004 Apr;59(4):324-7. doi: 10.1136/thx.2003.011577.

Reference Type BACKGROUND
PMID: 15047953 (View on PubMed)

Brower KS, Del Vecchio MT, Aronoff SC. The etiologies of non-CF bronchiectasis in childhood: a systematic review of 989 subjects. BMC Pediatr. 2014 Dec 10;14:4. doi: 10.1186/s12887-014-0299-y.

Reference Type BACKGROUND
PMID: 25492164 (View on PubMed)

LIU Xiu-yun, JIANG Zai-fang. The etiology of ninety-one children with bronchiecatsis. J Clin Pediatr, 2011, 29(2):127-129.

Reference Type BACKGROUND

CHEN Jun, DUO Li-kun, WANG Xiao-feng. Clinical analysis of 22 children with bronchiectasis. J Clin Pediatr, 2012, 30(1):51-54.

Reference Type BACKGROUND

WANG Hao,XU Bao-ping,LIU Xiu-yun,HU Ying-hui,REN Yi-xin,SHEN Kun-ling. Clinical characteristics and follow-up of bronchiectasis in children. Chinese Journal of Practical Pediatrics, 2014;29 (12):936-939.

Reference Type BACKGROUND

Other Identifiers

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BCHlung002

Identifier Type: -

Identifier Source: org_study_id

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