A Study of BMS-986171 in Healthy People to Assess Safety, to Measure Blood Levels of Drug, and to Find Out What the Drug Does to the Body
NCT ID: NCT02538874
Last Updated: 2017-05-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
275 participants
INTERVENTIONAL
2015-10-31
2016-11-05
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
TRIPLE
Study Groups
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Part A: Single Ascending Dose (SAD)
BMS-986171 or Placebo on specified days
BMS-986171
Placebo
Part B: Multiple Ascending Dose (MAD)
BMS-986171 or Placebo on specified days
BMS-986171
Placebo
Part C: Multiple Ascending Dose in Japanese subjects (J-MAD)
BMS-986171 or Placebo on specified days
BMS-986171
Placebo
Interventions
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BMS-986171
Placebo
Eligibility Criteria
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Inclusion Criteria
* BMI 30-40 (Part A or Part B); BMI 20-35 (Part C). BMI = weight (kg)/ \[height (m)\]
Exclusion Criteria
* Cannot tolerate subcutaneous injections, or having blood samples taken
* Smoking more than 10 cigarettes/day
* History of allergy to pegylated compounds or of hypersensitivity to protein based therapeutics.
* HIV, Hepatitis B virus (HBV) or Hepatitis C virus (HCV) infection.
* Pregnancy
21 Years
55 Years
ALL
Yes
Sponsors
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Bristol-Myers Squibb
INDUSTRY
Responsible Party
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Principal Investigators
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Bristol Myers Squibb
Role: STUDY_DIRECTOR
Bristol-Myers Squibb
Locations
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Profil Institute For Clinical Research, Inc.
Chula Vista, California, United States
Wcct Global, Llc
Cypress, California, United States
Countries
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Related Links
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BMS Clinical Trial Patient Recruiting
Investigator Inquiry Form
Other Identifiers
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MB007-005
Identifier Type: -
Identifier Source: org_study_id
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