Normative Values Laser Nociceptive Evoked Potentials Depending on the Age

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-02-29

Study Completion Date

2013-12-31

Brief Summary

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Different neurological damage may alter the pain conduction systems centrally (spinothalamic pathway) or peripherally (small caliber sensory fibers A delta and C). The laser thermal stimulation selectively stimulates the pain pathways and generates nociceptive signals conveyed to the cortex. Registering these cortical responses constitute the technical laser nociceptive evoked potentials. If these tests are routinely used, their interpretation must remain cautious especially in the elderly.

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Detailed Description

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Different neurological damage may alter the pain conduction systems centrally (spinothalamic pathway) or peripherally (small caliber sensory fibers A delta and C). The laser thermal stimulation selectively stimulates the pain pathways and generates nociceptive signals conveyed to the cortex. Registering these cortical responses constitute the technical laser nociceptive evoked potentials. If these tests are routinely used, their interpretation must remain cautious especially in the elderly. Normal values that are available have been obtained in young subjects. However, various studies have shown that the integration of nociceptive messages depended on age. The aim of this study was to establish normal values of nociceptive evoked potentials for each age group of 18 to 75 years.

Conditions

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Healthy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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healthy volunteers

Healthy volunteers are able to participate to this study. They must not have neurological troubles. They will have different stimulations :

* laser stimulations on lower limbs
* laser stimulations cervical
* 20 laser stimulations for each site on the upper limbs
* laser stimulations on face and neck

Group Type EXPERIMENTAL

laser stimulations on lower limbs

Intervention Type DEVICE

20 laser stimulations for each site : back foot, outer face of the legs, and anterior thigh

laser stimulations cervical

Intervention Type DEVICE

15 laser stimulations cervical areas below the ears.

20 laser stimulations for each site on the upper limbs

Intervention Type DEVICE

20 laser stimulations for each site : back of the hands and arms front face

laser stimulations on face and neck

Intervention Type DEVICE

15 lasers stimulations for each site : mandibular areas and areas below the ears.

Interventions

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laser stimulations on lower limbs

20 laser stimulations for each site : back foot, outer face of the legs, and anterior thigh

Intervention Type DEVICE

laser stimulations cervical

15 laser stimulations cervical areas below the ears.

Intervention Type DEVICE

20 laser stimulations for each site on the upper limbs

20 laser stimulations for each site : back of the hands and arms front face

Intervention Type DEVICE

laser stimulations on face and neck

15 lasers stimulations for each site : mandibular areas and areas below the ears.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* major

Exclusion Criteria

* Neurological history
* Neuralgia history (\> 3 months)
* Pathology can cause neuropathy (unbalanced thyroid dysfunction, diabetes, kidney failure, chronic hepatitis, HIV ...)
* Dermatological disorder known type of Lucite or photosensitivity
* Medical treatment analgesic, psychotropic or anti-epileptic underway
* Toxic acquired in the last 72 hours (alcohol, cannabis, other toxic ...)
* Pregnant women
* Incapacitate to stand still
* Participation in another biomedical research in the field of pain in the three months prior to inclusion.

Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes