Progressive Strength in Hand Osteoarthritis

NCT ID: NCT02528630

Last Updated: 2017-02-23

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE4
• Total Enrollment: 60 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2013-10-31
• Study Completion Date: 2015-10-31

Brief Summary

Background: Hand osteoarthritis (OA) is highly prevalent, affecting 55-70% of the population over 55 years with an age-related progressive increase. The OA of interphalangeal (IF) and carpometacarpal joints may have varying degrees of deformity associated with pain, decreased of grip and pinch strength, decreased range of motion and functional impairment. Systematic reviews and meta-analyzes have shown the beneficial effect of exercise for lower limb OA, however for hand OA exercise is still used based on recommendations based on clinical experience and low quality studies, not allowing a conclusion about the effects of exercise in pain, function and strength in hand OA patients.

Objective: assess the effectiveness of progressive resistance strength training program on pain, function and strength in hand OA patients.

Methods: diagnostic of hand OA according to American College of Rheumatology of at least 1year, age over 50 years, both genders, pain in IF joints between 3-8 cm on a 10-cm numerical pain scale (NPS). Sixty patients who meet the eligibility criteria were randomized into exercise group (EG) and control group (CG). Both groups performed a session regarding joint protection and energy conservation before randomization. The EG performed a progressive resistance strength training program for intrinsic muscles of the hand for 12 weeks. The outcome measures were NPS; Australian/Canadian (AUSCAN) Hand Osteoarthritis Index and Cochin Hand Functional Scale for hand function; grip and pinch strengthening using the Hydraulic Hand Dynamometer and a pinch gauge dynamometer and satisfaction with the treatment using a Likert scale. A blinded evaluator performed the evaluations at baseline, 6 and 12 weeks after treatment baseline.

Conditions

Hand Osteoarthritis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Exercise group

Performed a session regarding joint protection and energy conservation and a progressive resistance strength training program for intrinsic muscles of the hand for 12 weeks.

Group Type: EXPERIMENTAL

Progressive resistance strength training program

Intervention Type: OTHER

Patients undergo to strength training for intrinsic muscles of the hand twice a week, during 12 weeks.

Joint protection and energy conservation advice

Intervention Type: OTHER

A session regarding joint protection and energy conservation for hands was done before randomization.

Control group

Performed a session regarding joint protection and energy conservation

Group Type: ACTIVE_COMPARATOR

Joint protection and energy conservation advice

Intervention Type: OTHER

A session regarding joint protection and energy conservation for hands was done before randomization.

Interventions

Progressive resistance strength training program

Patients undergo to strength training for intrinsic muscles of the hand twice a week, during 12 weeks.

Intervention Type: OTHER

Joint protection and energy conservation advice

A session regarding joint protection and energy conservation for hands was done before randomization.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• diagnostic of hand OA according to american college of rheumatology of at least 1year;
• age over 50 years;
• both genders;
• pain in interphalangeal joints between 3-8 cm on a 10-cm numerical pain scale

Exclusion Criteria

• other joint disease in hands;
• other rheumatic systemic disease;
• surgery in hands or writs;
• exercise or joint injection in hands in the previous 3 months;
• disability to perform the exercises.

• Minimum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Federal University of São Paulo

OTHER

Sponsor Role: lead

Responsible Party

Michele Nery

Master Student

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Universidade Federal de Sao Paulo

São Paulo, São Paulo, Brazil

Countries

Brazil

Other Identifiers

CEP UNIFESP

Identifier Type: -

Identifier Source: org_study_id