Effect of a Specific Hand Intervention in Women With Arthralgia Secondary to Hormone Therapy Following Breast Cancer.

NCT ID: NCT06746376

Last Updated: 2024-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-04-01

Study Completion Date

2025-11-01

Brief Summary

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This study aims to evaluate the impact of a 12-week hand exercise program on pain, manual dexterity, and hand function in women experiencing hand joint pain (arthralgia) due to hormone therapy after breast cancer. Participants will be randomly assigned to either an intervention group, where they will perform specific hand exercises, or a control group, which will not receive any exercise program. Pain levels, hand function, and manual dexterity will be assessed before and after the intervention using questionnaires and functional tests. The goal is to determine whether targeted hand exercises can improve pain and daily hand use in this population.

Detailed Description

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This is a randomized, evaluator-blinded clinical trial that aims to determine the effects of a 12-week hand exercise program on pain, manual dexterity, and functional performance in women experiencing hand arthralgia due to hormone therapy following breast cancer. Participants will be randomly assigned to one of two groups: an intervention group performing specific hand exercises or a control group with no exercise intervention.

The primary outcome will be changes in hand pain levels assessed using the Brief Pain Inventory (BPI) and McCaffrey's Initial Pain Assessment Tool. Secondary outcomes will include functional performance measured with the DASH and ABILHAND questionnaires, as well as manual dexterity, speed, and coordination assessed through standardized tests (Purdue Pegboard Test, Box and Block Test, and Minnesota Rate of Manipulation Test).

The study will evaluate the potential benefits of targeted hand exercises for improving pain, dexterity, and quality of life in breast cancer survivors experiencing treatment-related hand symptoms.

Detailed Description

Study Design:

Type: Interventional (Clinical Trial) Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single-Blind (Evaluator) Primary Purpose: Treatment Duration: 12 weeks

Conditions

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Arthralgia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
The evaluator will be blinded to the patient's allocation

Study Groups

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Intervention

Description:

Participants assigned to the intervention group will undergo a 8-week supervised hand exercise program designed to improve pain, manual dexterity, and functionality. Sessions will last 45 minutes and occur once per week under the supervision of a qualified occupational therapist and one self-administrated home exercise session. The program includes three structured phases per session

Warm-Up Phase (10 minutes)

Gentle hand and wrist stretches Main Exercise Phase (25 minutes)

This phase focuses on strengthening, manual dexterity, and functional tasks:

Strengthening Exercises

Manual Dexterity Exercises

Functional Tasks (Simulated Activities of Daily Living - AVDs):

Cool-Down Phase (10 minutes)

8 weeks, with 45-minute sessions twice weekly.

Group Type EXPERIMENTAL

Occupational Therapy

Intervention Type OTHER

Description:

Participants assigned to the intervention group will undergo a 8-week supervised hand exercise program designed to improve pain, manual dexterity, and functionality.

Control

Description:

Participants in the control group will not receive any intervention during the study period. They will undergo the same assessments as the intervention group at baseline and after 8 weeks to evaluate changes over time.

Details:

The control group will serve as a comparison to determine the effects of time alone on pain, manual dexterity, and hand functionality in women with hormone therapy-related arthralgia.

Participants will continue their usual daily activities and standard care during the study period.

No specific exercises or additional therapies will be provided as part of the study.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Occupational Therapy

Description:

Participants assigned to the intervention group will undergo a 8-week supervised hand exercise program designed to improve pain, manual dexterity, and functionality.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Experiencing hand arthralgia as a result of hormone therapy (aromatase inhibitors or tamoxifen) following breast cancer.

Ability to communicate pain levels effectively. Ability to follow simple instructions to participate in the intervention and assessments.

Exclusion Criteria

Concurrent physiotherapy or occupational therapy specifically targeting the hand during the study.

Pre-existing diagnosis of arthritis or osteoarthritis in the hand before starting hormone therapy.

Presence of systemic diseases associated with hand arthralgia. Neurological conditions affecting hand movement.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Universidad Europea de Madrid

OTHER

Sponsor Role lead

Responsible Party

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Vanesa Abuín

Asistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Vanesa Abuín-Porras, PhD

Role: PRINCIPAL_INVESTIGATOR

Universidad Europea de Madrid

Locations

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Universidad Europea de Madrod

Villaviciosa de Odón, , Spain

Site Status

Countries

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Spain

Central Contacts

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Vanesa Abuín-Porras, PhD

Role: CONTACT

Phone: +34 676566073

Email: [email protected]

Nuria Muñoz-Bermúdez, PT

Role: CONTACT

Phone: +34 676566073

Email: nuria.muñ[email protected]

Facility Contacts

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Vanesa Abuín-Porras

Role: primary

Other Identifiers

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HANDPROJECT001

Identifier Type: -

Identifier Source: org_study_id