Does Pulmonary Rehabilitation Improve Frailty?

NCT ID: NCT02512874

Last Updated: 2020-06-23

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

65 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-07-21

Study Completion Date

2018-10-16

Brief Summary

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Frailty is a state of health with predisposition to adverse events, morbidity and mortality. Frailty consists of weakness, slowness, low physical activity, exhaustion, and wasting. Frailty is associated with increased hospitalizations and death in lung disease. It is unknown if pulmonary rehabilitation will improve frailty markers.

Detailed Description

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Individuals referred to pulmonary rehabilitation will be examined for frailty markers. After completing pulmonary rehabilitation, the same tests will be performed. The effects of pulmonary rehabilitation will be examined.

Conditions

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Disease, Pulmonary

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Pulmonary Rehabilitation

One arm study - all participants will go to pulmonary rehabilitation, received questionnaires, Dual-energy X-ray absorptiometry (DEXA) scans, Dynamometer and gait speed tests and activity measured through an activity monitor.

Group Type OTHER

Pulmonary Rehabilitation

Intervention Type OTHER

Measures of frailty taken before and after pulmonary rehabilitation.

Dynamometer

Intervention Type DEVICE

Grip Test

DEXA

Intervention Type RADIATION

Body Composition Testing

Gait Speed Test

Intervention Type OTHER

15 foot walk test

Activity Monitor

Intervention Type DEVICE

Measures energy expenditure and activity

Questionnaires

Intervention Type OTHER

Health-related questionnaires measuring self-reported exhaustion, emotions and disease symptoms.

Interventions

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Pulmonary Rehabilitation

Measures of frailty taken before and after pulmonary rehabilitation.

Intervention Type OTHER

Dynamometer

Grip Test

Intervention Type DEVICE

DEXA

Body Composition Testing

Intervention Type RADIATION

Gait Speed Test

15 foot walk test

Intervention Type OTHER

Activity Monitor

Measures energy expenditure and activity

Intervention Type DEVICE

Questionnaires

Health-related questionnaires measuring self-reported exhaustion, emotions and disease symptoms.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Referred for pulmonary rehabilitation
* consenting to research

Exclusion Criteria

-Under 18 years of age
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Heart, Lung, and Blood Institute (NHLBI)

NIH

Sponsor Role collaborator

Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Cassie C. Kennedy, M.D.

Consultant for Critical Care Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Cassie Kennedy, MD

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic in Rochester

Rochester, Minnesota, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Related Links

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Other Identifiers

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K23HL128859

Identifier Type: NIH

Identifier Source: secondary_id

View Link

15-001230

Identifier Type: -

Identifier Source: org_study_id

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