Cone-beam CT Guided Microcoil Localization of Pulmonary Nodules During Video Assisted Thoracic Surgery(VATS)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-06-30

Study Completion Date

2026-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The Guided Therapeutics (GTx) program at the University Health Network is a network of clinicians, scientists, and engineers focused on the development and translation of image-guided technologies focused on minimally-invasive, adaptive therapies. Technologies developed within the GTx program include a portable intra-operative cone-beam CT (in collaboration with Siemens) that has been evaluated in clinical trials for head and neck surgery. The intraoperative imaging has been integrated with tracking and navigational tools and optical imaging to provide a general "surgical dashboard" that is used to improve the accuracy of surgical resection.

A recent addition to the GTx program is the development of the GTx OR, located within the general operating room of the Toronto General Hospital. The GTx OR houses 2 complimentary advance technologies: the Siemens Zeego and the Siemens Somotom Flash CT. The dual-energy Somatom Flash provides a "gold-standard" in CT imaging, while the Zeego provides excellent 3D Cone-beam CT with robotic placement for flexible integration within the operating environment. Together, the integration of these 2 components into a single OR enables critical evaluation of the limits of CT imaging technology for surgical guidance.

This study will be conducted using solely the Cone-beam CT (Zeego) for percutaneous placement and localization of markers for resection of small pulmonary nodules during VATS.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Preoperative Computed Tomography-guided Localization for Lung Nodules: Localization Needle Versus Coil

NCT05183945

Lung; Node

UNKNOWN NA

Removal of Lung Nodules After Being Marked With a Microcoil

NCT00323089

Lung Cancer

COMPLETED NA

Comparing of Microcoil Localization and Hook Wire Localization for Resectable Pulmonary Small Nodules

NCT02908646

Thoracic Surgery

UNKNOWN PHASE3

Percutaneous Localization: Open-label Registry of Thoracic Surgery

NCT04066699

Lung Lesion(s) Requiring Evaluation Pulmonary Metastasis Pulmonary Nodule, Solitary +1 more

COMPLETED

Study to See if Microcoil Insertion Reduces the Rate of Open Thoracotomy for Removal of Lung Nodules

NCT01028417

Lung Cancer

COMPLETED PHASE3

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Lung Cancer

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Lung cancer

Group Type OTHER

Cone Beam CT localization and placement of microcoil

Intervention Type OTHER

Cone Beam CT localization and placement of microcoil

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Cone Beam CT localization and placement of microcoil

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Any adult patient age 18 and older with lung nodules who are candidates for microcoil localization prior to VATS wedge resection

Exclusion Criteria

* Patients that are unable to give informed consent
* Patients that are unable to tolerate general anesthesia
* Patients who are pregnant or patients that believe they are pregnant
* Patients with implantable devices susceptible to Radio Frequency (RF) fields
* Severely obese patients

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No