Tissue Collection Protocol for Gastroesophageal Cancers

NCT ID: NCT02495337

Last Updated: 2025-05-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-05-31

Study Completion Date

2030-12-31

Brief Summary

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This proposed collection of primary tumor cells lines will benefit esophageal cancer research within the University Health Network. This collection of gastro-esophageal tumor samples will be used to grow primary tumor cell lines, which will provide researchers with ready samples of various gastro-esophageal cancers. This will help to address the issue of access to these cell lines due to the limited number of patients with gastro-esophageal tumors, and high rates of contamination.

Detailed Description

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Samples will be collected during surgery, EGD, or other biopsy. The surgeon will resect a sample for the research coordinator and/or fellow who will collect the sample and take it back to the lab for processing. Samples collected will be in excess of standard samples that are sent for pathology. The surgeon will make sure that excess samples will not affect pathological diagnosis. In addition samples may be purchased from the National Cancer Institute's Cooperative Human Tissue Network.

Conditions

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Esophageal Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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TIssue Collection

Only one arm will be used to collect tissue from Esophageal Adenocarcinoma

Tissue Collection

Intervention Type OTHER

Interventions

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Tissue Collection

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with esophagogastric cancer and/or GERD +/- Barrett's esophagus who will undergo surgery and/or EGD as standard of care.

Exclusion Criteria

* Patients who are not well enough to undergo surgery or EGD as standard of care.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Health Network, Toronto

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jonathan Yeung

Role: PRINCIPAL_INVESTIGATOR

University Health Network, Toronto

Locations

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University Health Network: Toronto General Hospital

Toronto, Ontario, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Frances Allison

Role: CONTACT

416-340-5446

Facility Contacts

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Frances Allison

Role: primary

416-340-5446

Other Identifiers

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14-8514

Identifier Type: -

Identifier Source: org_study_id

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