Regenerative Cellular Therapies, Physiology, Pathology and Developmental Biology
NCT ID: NCT02469207
Last Updated: 2016-07-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
50 participants
OBSERVATIONAL
2016-01-31
2020-06-30
Brief Summary
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Detailed Description
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The study aims are:
* To examine function and the immune response to stem cells and their differentiated progeny as well as development of immunomodulatory approaches to prevent their rejection.
* Generation of induced pluripotent stem cells (iPSCs) and their subsequent differentiation into functional cells as potential therapies.
* Generation of differentiated cells from native adult stem cells as cellular therapies.
* Investigation of organ physiology.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Deceased organ donors
Patients with consent for organ donation towards transplantation and research. Organs not used for transplantation will be used for this study if determined appropriate and necessary.
Removal of tissue post-mortem
Interventions
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Removal of tissue post-mortem
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
16 Years
92 Years
ALL
Yes
Sponsors
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University of Cambridge
OTHER
Cambridge Stem Cell Institute, Cambridge
UNKNOWN
Anne McLarent Laboratory of Regenerative Medicine, Cambridge
UNKNOWN
The Gurdon Institute, Cambridge
UNKNOWN
Sanger Institure, Cambridge
UNKNOWN
Institute of Metabolic Science, Cambridge
UNKNOWN
MRC Mitochondrial Biology Unit, Cambridge
UNKNOWN
Cambridge University Hospitals NHS Foundation Trust
OTHER
Responsible Party
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Dr. Kourosh Saeb-Parsy
Mr Kourosh Saeb-Parsy
Principal Investigators
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Kourosh Saeb-Parsy, PhD, FRCS
Role: PRINCIPAL_INVESTIGATOR
Cambridge Univeristy Hospitals
Locations
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Addenbrooke's Hospital
Cambridge, , United Kingdom
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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15/EE/0152
Identifier Type: OTHER
Identifier Source: secondary_id
A093532
Identifier Type: -
Identifier Source: org_study_id
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