Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty (TKA) Using the SPRINT System

NCT ID: NCT02468934

Last Updated: 2018-09-04

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-10-22

Study Completion Date

2017-07-17

Brief Summary

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The purpose of this study is to determine if electrical stimulation (small levels of electricity) can safely and effectively reduce pain following total knee replacement (or total knee arthroplasty (TKA)). This study involves a device called the SPRINT System. The SPRINT System delivers mild electrical stimulation to nerves in the leg that received the knee replacement. The SPRINT System includes a small wire (called a "lead") that is placed through the skin in the upper leg. It also includes a device worn on the body that delivers stimulation (called the SPRINT Stimulator).

Detailed Description

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Conditions

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Total Knee Replacement Total Knee Arthroplasty Pain Postoperative Pain Orthopedic Disorders

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Peripheral Nerve Stimulation

All study subjects will have up to 2 Smartpatch Leads placed in their leg that underwent total knee replacement, will use the SPRINT Peripheral Nerve Stimulation (PNS) System, and will receive electrical stimulation.

Group Type EXPERIMENTAL

SPRINT Peripheral Nerve Stimulation (PNS) System

Intervention Type DEVICE

The SPRINT System is an Investigational Device which delivers mild electrical stimulation to nerves in the leg that underwent lead placement. The SPRINT System includes a small wire (called a "Lead") that is placed through the skin in the upper leg. It also includes a device worn on the body that delivers stimulation (called the SPRINT Stimulator).

Interventions

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SPRINT Peripheral Nerve Stimulation (PNS) System

The SPRINT System is an Investigational Device which delivers mild electrical stimulation to nerves in the leg that underwent lead placement. The SPRINT System includes a small wire (called a "Lead") that is placed through the skin in the upper leg. It also includes a device worn on the body that delivers stimulation (called the SPRINT Stimulator).

Intervention Type DEVICE

Other Intervention Names

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Smartpatch Smartpatch System SPRINT System

Eligibility Criteria

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Inclusion Criteria

* At least 21 years old
* Scheduled to undergo a primary unilateral total knee replacement procedure

Exclusion Criteria

* Body Mass Index (BMI) \> 40 kg/m2
* Compromised immune system based on medical history
* History of valvular heart disease
* Implanted electronic device
* Joint or overlying skin infection of the affected limb
* History of recurrent skin infections
* Bleeding disorder
* Allergy to skin surface electrodes and/or medical-grade adhesive tapes
* Pregnant
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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SPR Therapeutics, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University of California San Diego

La Jolla, California, United States

Site Status

Duke University Medical Center

Durham, North Carolina, United States

Site Status

Joint Implant Surgeons

New Albany, Ohio, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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0141-CSP-000

Identifier Type: -

Identifier Source: org_study_id

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