The Effect of Melatonin on Gene Expression and Activity of the Sirt1 and Its Target Genes Catalase and MnSOD in Multiple Sclerosis Patients and Healthy Subjects
NCT ID: NCT02463318
Last Updated: 2017-05-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
34 participants
INTERVENTIONAL
2012-09-30
2015-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
SINGLE_GROUP
BASIC_SCIENCE
NONE
Study Groups
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Multiple slerosis
Melatonin,,one millimolar,one micromolar,one nanomolar, 12 hr treatment.
Melatonin
Melatonin is used for healthy subjects and multiple sclerosis patients
Healthy subjects
Melatonin,one millimolar,one micromolar,one nanomolar, 12 hr treatment. hydrogen peroxide, 250 micromollar,2 hr treatment
Melatonin
Melatonin is used for healthy subjects and multiple sclerosis patients
Hydrogen peroxide
Hydrogen peroxide is only used for healthy subjects
Interventions
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Melatonin
Melatonin is used for healthy subjects and multiple sclerosis patients
Hydrogen peroxide
Hydrogen peroxide is only used for healthy subjects
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
\-
20 Years
40 Years
FEMALE
Yes
Sponsors
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Tehran University of Medical Sciences
OTHER
Responsible Party
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Principal Investigators
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Mohammad Ali Sahraian, Neurologist
Role: STUDY_DIRECTOR
Tehran University of Medical Sciences
Solaleh Emamgholipour, PhD Student
Role: PRINCIPAL_INVESTIGATOR
Tehran University of Medical Sciences
Locations
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Solaleh Emamgholipour
Tehran, , Iran
Countries
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Other Identifiers
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91-01-30-17019
Identifier Type: -
Identifier Source: org_study_id
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