Prevention of Healthcare Associated Infections in Bone Marrow Transplant Patients

NCT ID: NCT02463214

Last Updated: 2019-04-17

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 45 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2015-09-30
• Study Completion Date: 2018-03-31

Brief Summary

This study involves sampling bone marrow transplant patients, hospital workers and the patient room for microbes using swabs and other techniques. We send these samples to the laboratory, where they will use state-of-the art technology to identify and relate the microbes to each other. This study also involves putting copper, nickel, or titanium into some hospital rooms, and seeing whether these metals influences the growth of microbes. Some equipment in the hospital room, such as faucets and soap dispensers will be replaced by sensor-based (e.g. touchless) controls.

Detailed Description

Bacteria and other microbes are everywhere, the majority of which are harmless. They live on our bodies, on everyday objects, in food, and in our environment. They are passed around through the many interactions with other people and our surroundings. Some are even beneficial, helping us digest our food or protecting us from infections caused by harmful microbes.

In rare instances, some of the harmful microbes can cause infections. When a microbe causes an infection while we are in healthcare facilities, they are called "Healthcare-associated infections", or "HAIs". Examples that you may have heard of include Clostridium difficile, and MRSA (methicillin-resistant Staphylococcus aureus). Vancouver General Hospital already has some of the lowest HAI rates in the country. We have dedicated hospital workers that do a great job at preventing HAIs, but we are always looking for ways to be even better.

Conditions

Transplantation Infection

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

Standard Room

Standard bone marrow transplant recovery, single occupancy, room

Group Type: NO_INTERVENTION

No interventions assigned to this group

Engineered Room

Single occupancy bone marrow transplant recovery room, engineered with touchless devices, and surfaces coated with either copper or titanium dioxide.

Group Type: EXPERIMENTAL

Engineered Room

Intervention Type: OTHER

Touchless devices:

Hand sanitizers, faucets, paper towel dispensers, call devices, Ultraviolet C Aseptix™ Disinfection devices above bathroom doors

Copper products:

Room and bathroom entrance door hardware, over bed table and bed side table surfaces, chair metal arms, wardrobe handles and knobs, weigh scale, sinks, grab bars, light switch panels, toilet flush handles, faucets and handles, patient bed rails.

Titanium dioxide paint:

Room walls, head walls, light switches, bathroom wall shelves, toilet tank and bowl, head wall unit fixed equipment, television remote and Bed Control remote

Interventions

Engineered Room

Touchless devices:

Hand sanitizers, faucets, paper towel dispensers, call devices, Ultraviolet C Aseptix™ Disinfection devices above bathroom doors

Copper products:

Room and bathroom entrance door hardware, over bed table and bed side table surfaces, chair metal arms, wardrobe handles and knobs, weigh scale, sinks, grab bars, light switch panels, toilet flush handles, faucets and handles, patient bed rails.

Titanium dioxide paint:

Room walls, head walls, light switches, bathroom wall shelves, toilet tank and bowl, head wall unit fixed equipment, television remote and Bed Control remote

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• undergoing allogenic bone marrow transplant for acute myeloid leukemia
• will be admitted to the leukemia and bone marrow transplant service at Vancouver General Hospital
• admission to the ward anticipated to be approximately 28 days

• undergoing allogenic bone marrow transplant for acute myeloid leukemia
• caring for patient enrolled in the study as a primary nurse

Exclusion Criteria

• allergies to copper, nickel or titanium
• patients admitted for stays anticipated to be less than 28 days

• allergies to copper, nickel or titanium

• Minimum Eligible Age: 19 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Vancouver Coastal Health Research Institute

OTHER

Sponsor Role: collaborator

University of British Columbia

OTHER

Sponsor Role: lead

Responsible Party

Linda Hoang

Medical Microbiologist, BC Centre for Disease Control

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Linda Hoang, MD FRCPC

Role: PRINCIPAL_INVESTIGATOR

The University of British Columbia

Elizabeth Bryce, MD FRCPC

Role: PRINCIPAL_INVESTIGATOR

The University of British Columbia

Patrick Tang, MD PhD FRCPC

Role: PRINCIPAL_INVESTIGATOR

Sidra Medicine

Locations

Vancouver General Hospital

Vancouver, British Columbia, Canada

Countries

Canada

Other Identifiers

H15-00662

Identifier Type: -

Identifier Source: org_study_id