Neural Changes Associated With a Mindfulness-based Intervention for Young Adults With Childhood Maltreatment

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

43 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-08-01

Study Completion Date

2016-07-21

Brief Summary

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Childhood trauma is remarkably prevalent, and it has long lasting impact on mental health and neural development. This trial aims to see whether the 8-week mindfulness based intervention can reduce stress related psychological symptoms for young adults with childhood maltreatment, and whether it can promote neural plasticity.

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Detailed Description

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This study recruits young adults with childhood adversity; enrolled subjects either receive an 8-week mindfulness based intervention, or wait for 8 weeks before receiving the intervention. MRI and a battery of self report questionnaires will be administered before and after the intervention; subjects on the waiting list will undergo the same research procedures at the same time as subjects in the intervention group. Primary hypotheses include improved hippocampal plasticity, increased mindfulness and reduced stress and related psychological symptoms.

Conditions

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Depression Anxiety PTSD Trauma, Psychological

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Mindfulness group

This arm receives an 8-week mindfulness based behavioral intervention program.

Group Type EXPERIMENTAL

Mindfulness based intervention

Intervention Type BEHAVIORAL

The intervention is an 8-week structured mindfulness based behavioral intervention program that teaches mindfulness meditation, mindful yoga and psychological knowledge about stress.

Waitlist control group

This arm waits while the mindfulness group receives their intervention, and then receives the mindfulness based intervention after their waiting period.

Group Type OTHER

Mindfulness based intervention

Intervention Type BEHAVIORAL

The intervention is an 8-week structured mindfulness based behavioral intervention program that teaches mindfulness meditation, mindful yoga and psychological knowledge about stress.

Interventions

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Mindfulness based intervention

The intervention is an 8-week structured mindfulness based behavioral intervention program that teaches mindfulness meditation, mindful yoga and psychological knowledge about stress.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Experience of childhood maltreatment
* With current age between 19 to 35 years old
* With current symptoms of depression or anxiety or PTSD or significant general stress.

Exclusion Criteria

* History of psychiatric disorders with psychotic features
* Suicidal attempts during the past six months
* Neurological disorders
* Prior history with the mindfulness based stress reduction program or other systematic meditation programs.

Minimum Eligible Age

19 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes