Topiramate and Cerebrovascular Response in Migraineurs

NCT ID: NCT02424318

Last Updated: 2015-04-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

19 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-12-31

Study Completion Date

2010-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to evaluate the effect of topiramate on cerebrovascular reactivity and mean flow velocity to photic stimulation in migraineurs.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Migraine Disorders

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Topiramate

topiramate 25mg twice for 1 week -\> topiramate 50mg twice for 7 weeks

Group Type EXPERIMENTAL

Topiramate

Intervention Type DRUG

topiramate 25mg twice 1 week -\> topiramate 50mg twice 7 weeks

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Topiramate

topiramate 25mg twice 1 week -\> topiramate 50mg twice 7 weeks

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* aged 18 to 65 years
* newly-diagnosed patients with migraine without aura (International Headache Society classification)
* symptom frequency (at least 2 episodes of migraine attack/month)

Exclusion Criteria

* prior use of preventive medication
* patients with cardiovascular risk factors (hypertension, diabetes, hyperlipidemia, smoking)
* patients who take antihypertensive agent or antidepressant
* patients who were pregnant, breast-feeding or actively smoking
* patients with neurological or cerebrovascular diseases
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

SMG-SNU Boramae Medical Center

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Hyunwoo Nam

SMG-SNU Boramae Medical Center

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Hyunwoo Nam, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

SMG-SNU Boramae Medical Center

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

06-2008-71

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.