Predicting Relapse After Cocaine Inpatient Cessation

NCT ID: NCT02416050

Last Updated: 2023-03-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

87 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-02-03

Study Completion Date

2022-01-03

Brief Summary

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Can brain MRI at entry of cocaine inpatient cessation attempt predict relapse during a three month follow-up ? Hypothesis : White matter losses in the prefrontal cortex are associated with relapse to cocaine use.

Detailed Description

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A multivariate model using MRI parameters, craving score, impulsivity score, and neuropsychological testing results will be tested to predict relapse or continuous abstinence three month after cocaine inpatient cessation attempt.

Conditions

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Cocaine Dependence Cocaine Use Disorder

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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Brain MRI imagery

Brain MRI performed during the first week of inpatient cocaine cessation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* cocaine dependent patient requiring inpatient cessation
* 18 years old and older
* giving his/her consent to come back for visits up to three months
* having a social insurance

Exclusion Criteria

* minor
* under guardianship
* restraint hospitalization
* contraindication to brain MRI
* pregnant women
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Florence VORSPAN, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Assistance Publique - Hôpitaux de Paris

Locations

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Service de Psychiatrie, Hôpital Fernand Widal

Paris, , France

Site Status

Countries

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France

Other Identifiers

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2014-A01169-38

Identifier Type: OTHER

Identifier Source: secondary_id

P120125

Identifier Type: -

Identifier Source: org_study_id

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