Brain Metabolism in Polycystic Ovary Syndrome

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

7 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-03-31

Study Completion Date

2014-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to investigate whether higher insulin resistance in young women with Polycystic ovary syndrome (PCOS) is associated with reduced cerebral metabolic rate of glucose (CMRglu). Brain volumes using magnetic resonance imaging (MRI) and quantitative cerebral glucose uptake using dynamic positron emission tomography (PET) were obtained.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Functional Study of the Hypothalamus in Magnetic Resonance Imaging (MRI) in Polycystic Ovary Syndrome (PCOS)

NCT03043924

Polycystic Ovary Syndrome

COMPLETED NA

Post-Prandial Liver Glucose Metabolism in PCOS

NCT03041129

Polycystic Ovarian Syndrome Obesity Hepatic Steatosis

COMPLETED

The Study of Polycystic Ovary Syndrome (PCOS) and Questionnaire

NCT01256970

Polycystic Ovary Syndrome

COMPLETED

The Study of Polycystic Ovary Syndrome(PCOS) With Gene and Questionnaire

NCT01114659

Polycystic Ovary Syndrome

COMPLETED

Nutritional and Metabolic Correlates of Ovarian Morphology in Women With Polycystic Ovary Syndrome

NCT01927471

Polycystic Ovary Syndrome (PCOS) Menstrual Irregularity

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

MRI and FDG PET scan for each participant were obtained within an average time frame of 3 weeks. Isulin resistance were assessed with the updated homeostasis model assessment (HOMA2-IR).

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Insulin Resistance

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

POLYCYSTIC OVARY SYNDROME (PCOS)

FDG PET scan,T1-weight MRI and blood were obtained for each participant

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Diagnosis of PCOS
* Age ≤ 35 y
* BMI ≤ 35

Exclusion Criteria

* Taking medications for diabetes or insulin-sensitizing drugs
* Drug addictions
* Psychiatric illness
* Smoking
* Overt evidence of heart, liver or renal disease

Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No