MedDataX Logo

A Comparative Analysis of Arterial Blood Flow in Unexplained Infertility, Tubal Infertility and Fertile Groups

NCT ID: NCT02393235

Last Updated: 2015-07-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

217 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-03-31

Study Completion Date

2015-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Factors affecting the success of the treatment of infertility can evaluate before and after embryo transfer in two stages. Most of the patients reach the embryo transfer stage. Unfortunately, the investigators are able to intervene very few of the factors that will affect the success of the post-transfer. All factors and treatments that affect the implantation is vital to identify. Basically, healthy vasculature is essential for a successful implantation. The investigators will try to understand relationship between vascular resistance and type of infertility. The investigators will examine whether the effect of the ovarian uterine and spiral artery resistance over infertility.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Baseline and First Trimester Uterine Artery Doppler Velocimetry to Predict Poor Obstetric Outcomes in IVF

NCT05661539

Infertility, Female
UNKNOWN

The Effect of Embryo Transfer Technique on Pregnancy Outcomes in HRT-FET Cycles

NCT05564312

Infertility
UNKNOWN

The Effect of Baseline Bilateral Uterine Artery Doppler Velocimetry on Obstetric Outcomes in HRT-FET Cycles

NCT05526014

Infertility
UNKNOWN

Comparison of Blood Flow in the Arteriae Uterinae in Ovarian Stimulation Cycles

NCT03887728

Endometrial Receptivity
COMPLETED

The Accuracy of Endometrial Ultrasound to Predict Implantation

NCT03860636

Infertility, Subfertility
COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

In this study the investigators will examine whether the alterations of doppler indices in the uterine, ovarian and spiral arteries can help to explain tubal or unexplained infertility as a standard screening method. Patients in unexplained-tubal infertility groups were treated in our IVF clinic. Patients will be invited to the hospital according to the criteria of the study. Fertile patients will be selected according to the criteria for patients who have come for the annual smear control. The study hypothesis is that the resistance in ovarian, uterine and spiral artery doppler will be higher in cases with tubal and unexplained infertility as opposed to low resistance in fertile women.Ovarian, uterine and spiral artery pulsatility index (PI = (peak systolic velocity - end diastolic velocity) / time averaged velocity and resistance index ( RI= (peak systolic velocity - end diastolic velocity) / peak systolic velocity ) will measure with doppler ultrasonography in the mid-luteal phase ( 21th day). Measured values are to be compared.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Infertility

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

unexplained infertility(n:75)

Ovarian, uterine and spiral artery pulsatility index and resistance index will measure with doppler ultrasonography in the mid-luteal phase. ( 21th day)

doppler ultrasonography

Intervention Type OTHER

Ovarian, uterine and spiral artery pulsatility index and resistance index will measure

tubal infertility(n:75)

Ovarian, uterine and spiral artery pulsatility index and resistance index will measure with doppler ultrasonography in the mid-luteal phase. ( 21th day)

doppler ultrasonography

Intervention Type OTHER

Ovarian, uterine and spiral artery pulsatility index and resistance index will measure

fertile group(n:75)

Ovarian, uterine and spiral artery pulsatility index and resistance index will measure with doppler ultrasonography in the mid-luteal phase. ( 21th day)

doppler ultrasonography

Intervention Type OTHER

Ovarian, uterine and spiral artery pulsatility index and resistance index will measure

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

doppler ultrasonography

Ovarian, uterine and spiral artery pulsatility index and resistance index will measure

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* unsuccessful infertility treatment
* normal prolactin levels
* normal thyroid stimulation hormone levels
* no ovarian or pelvic surgery history

Exclusion Criteria

* To have systemic diseases
* receive medical treatments which may influence the clearance or excretion of gonadotropins and sex steroids
Minimum Eligible Age

22 Years

Maximum Eligible Age

37 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Bagcilar Training and Research Hospital

OTHER_GOV

Sponsor Role collaborator

Suleymaniye Birth And Women's Health Education And Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Ali G Zebitay, M.D.

Role: PRINCIPAL_INVESTIGATOR

Suleymaniye Birth And Women's Health Education And Research Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Suleymaniye Birth And Women's Health Education And Research Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Turkey (Türkiye)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

AGZ1-UN-DOP

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Ultrasound Study by Texturization as a Predictor of Pregnancy in Oocyte Donation Programs
NCT03507322 WITHDRAWN
Evaluation of Blastocyst Morphology and Quality in Patients With Embryo Transfer at the Blastocyst Stage
NCT05510557 UNKNOWN
Assesment of Embryo Viability and Re-expansion After Thawing in Blastocyst Stage Embryos
NCT05474833 UNKNOWN
Success Rate Natural Cycles Versus Modified Natural Cycles in Frozen Embryos
NCT03798886 UNKNOWN
Perifollicular Doppler in Natural Cycle In Vitro Fertilization
NCT01668212 COMPLETED
The Effect of Follicular Flushing on Oocyte Retrieval Rate and Embryo Quality
NCT05584436 ACTIVE_NOT_RECRUITING
Influence of Post-thaw Embryo Culture Interval on Assisted Reproduction Success Rates
NCT03381001 COMPLETED NA
Does the Air-bubble Location Influence on the Implantation Rate
NCT04574310 COMPLETED
Prediction of Ovarian Response
NCT00557687 COMPLETED
Endometrial Local Injury to Improve the Outcome of Embryo Transfer
NCT02306395 UNKNOWN NA
Embryotransfer Operator and Pregnancy Rate
NCT03561129 COMPLETED
Female Fertility, Environmental Agents and Stress Oxidant
NCT04866329 RECRUITING
Pregnancy Success Rates of Acupuncture for in Vitro Fertilization
NCT03572608 UNKNOWN NA
Predictive Value of Th1, Th2 and Th17 Cytokines on the Success of Embryo Implantation (ImmuNoFertilité)
NCT05783349 COMPLETED NA
Stress in Couples Undergoing Assisted Reproduction Technology With Different Cycles and Its Impact on Pregnancy Outcomes
NCT05055245 UNKNOWN
Follicular Flushing Versus Direct Aspiration
NCT03354858 COMPLETED
Endometrial Injury and Single Embryo Transfer
NCT01851876 COMPLETED NA
Extended Culture of Day 3 to Day 5 Frozen Thawed Day 3 Embryos Versus Day 5 Frozen-Thawed Embryos
NCT05858333 COMPLETED NA
The Effect of the Mediterranean Diet on Fatty Acids in Biological Fluids of Women Undergoing Infertility Treatment
NCT06559904 COMPLETED NA
Effect of Embryo Migration in Fresh Oocyte Donation Cycles
NCT04855669 UNKNOWN
Swim up and Gradient Methods Used in Assisted Reproduction Techniques on DNA Fragmentation of Spermatozoa
NCT01859520 COMPLETED NA
Endometrial Injury Increases Implantation and Pregnancy Rates
NCT01340560 COMPLETED NA
Comparison of Clinical Outcomes in Fresh Cycle With Single Blastocyst Stage and Double Cleavage-stage Embryos: a Single-center, Non-blind, Randomized Controlled Study
NCT05632731 UNKNOWN NA
Synchronizing Blastocyst in Frozen Embryo Transfer
NCT03128970 COMPLETED NA
What is the Optimal Cycle Regimen for Frozen- Thawed Embryo Transfer Cycles
NCT03954587 TERMINATED