Clinical Trial of Vagus Nerve Stimulation for Treatment of Refractory Epilepsy
NCT ID: NCT02378792
Last Updated: 2016-10-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
EARLY_PHASE1
300 participants
INTERVENTIONAL
2014-08-31
2017-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Rechargeable Implantable Vagus Nerve Stimulation System for Drug-Refractory Epilepsy
NCT05993117
Trial to Evaluate the Safety and Effectiveness of Vagus Nerve Stimulation for Children With Refractory Epilepsy
NCT03062514
Transcutaneous Non-invasive Stimulation of the Vagus Nerve for the Treatment of Difficult-to-treat Epilepsy
NCT01178437
Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Refractory Epilepsy
NCT02602899
Transcutaneous Auricular Vagus Nerve Stimulation for Pediatric Epilepsy
NCT02004340
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Vagus Verve Stimulation is on
Vagus Nerve Stimulation
Vagus Nerve Stimulator
Placebo Vagus Verve Stimulation is off
Vagus Nerve Stimulation
Vagus Nerve Stimulator
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Vagus Nerve Stimulation
Vagus Nerve Stimulator
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
2. Having tried at least two appropriate anti-epileptic drugs (AEDs) tested to tolerance or to blood levels at upper end of the target range of which at least 2 have been tolerated at normal dose.
3. At least 1 seizure per month.
4. In good health except epilepsy.
5. With normal MMSE score
6. Patients or his(her) familyscould understand this method and sign the informed consent 7）Patients with good compliance and could complete postoperative follow-up.
Exclusion Criteria
2. The vagus nerve lesion and damage
3. Tumor, cardiopulmonary anomaly, progressive neurological diseases, asthma，mental disease，pepticulcer，diabetes Type 1，bad health etc, and other surgical contraindication
4. Alcohol addiction, smoking, and sleep-related breathing disorders
6 Years
60 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Beijing Tiantan Hospital
OTHER
Beijing Pins Medical Co., Ltd
INDUSTRY
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Beijing Tiantan Hospital
Beijing, Beijing Municipality, China
The first hospital of jilin university
Changchun, Jilin, China
The general of shenyang military
Shenyang, Liaoning, China
Qilu hospital of shandong university
Jinan, Shandong, China
The second affiliated hospital zhejiang university school of medicine
Hangzhou, Zhejiang, China
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Li Luming, PhD
Role: CONTACT
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Kan Xu, MD
Role: primary
Jiqing Qiu
Role: backup
Guobiao Liang, MD
Role: primary
Guanqian Yuan
Role: backup
Shujun Xu, MD
Role: primary
Wenhua Zhang
Role: backup
Weiming FU, MD
Role: primary
Junming Zhu
Role: backup
References
Explore related publications, articles, or registry entries linked to this study.
Liu H, Zhan P, Meng F, Wang W. Chronic vagus nerve stimulation for drug-resistant epilepsy may influence fasting blood glucose concentration. Biomed Eng Online. 2020 May 29;19(1):40. doi: 10.1186/s12938-020-00784-1.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
PINS-012
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.