Trial Outcomes & Findings for Portable EMG-triggered Hand Robot for Individuals After Stroke (NCT NCT02364700)

NCT ID: NCT02364700

Last Updated: 2017-07-12

Results Overview

The FMA is a performance based evaluation of upper limb impairment of the affected arm after stroke. Scoring is based on an ordinal scale of 0 (no movement) to 2 (normal movement). Scoring is based on sum of 30 items, ranging from 0-60.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

12 participants

Primary outcome timeframe

baseline to 6 weeks (discharge)

Results posted on

2017-07-12

Participant Flow

Participant milestones

Participant milestones
Measure
Interventional Group
This is a single group, interventional pilot study. Participants will received 6-week hand training on the HOH device. Subjects will receive arm training 3x/week for 6 weeks
Overall Study
STARTED
12
Overall Study
COMPLETED
12
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Portable EMG-triggered Hand Robot for Individuals After Stroke

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Interventional Group
n=12 Participants
This is a single group, interventional pilot study. All participants will receive 6-week hand training on the HOH device. Subjects will receive arm training 3x/week for 6 weeks.
Age, Continuous
57.1 years
STANDARD_DEVIATION 10.2 • n=5 Participants
Sex: Female, Male
Female
10 Participants
n=5 Participants
Sex: Female, Male
Male
2 Participants
n=5 Participants
Box and Blocks
5.67 number of blocks
STANDARD_DEVIATION 10.36 • n=5 Participants
Arm Motor Ability Test (AMAT)
2.13 units on a scale
STANDARD_DEVIATION .50 • n=5 Participants
Fugl-Meyer Assessment (FMA)
20.75 units on a scale
STANDARD_DEVIATION 7.90 • n=5 Participants
Stroke Upper Limb Capacity Scale (SULCS)
5.33 units on a scale
STANDARD_DEVIATION 2.15 • n=5 Participants
Stroke Impact Scale-Hand Subscale
11.50 units on a scale
STANDARD_DEVIATION 4.91 • n=5 Participants
Dynamometry
7.96 kilograms
STANDARD_DEVIATION 6.24 • n=5 Participants

PRIMARY outcome

Timeframe: baseline to 6 weeks (discharge)

The FMA is a performance based evaluation of upper limb impairment of the affected arm after stroke. Scoring is based on an ordinal scale of 0 (no movement) to 2 (normal movement). Scoring is based on sum of 30 items, ranging from 0-60.

Outcome measures

Outcome measures
Measure
Interventional Group
n=12 Participants
This is a single group, interventional pilot study. Participants will received 6-week hand training on the HOH device. Subjects will receive arm training 3x/week for 6 weeks
Fugl-Meyer Assessment of Upper Extremity (FMA)
22.50 units on a scale
Standard Deviation 9.47

PRIMARY outcome

Timeframe: Baseline to 6 weeks (discharge)

The AMAT is performance based measure of functional ability of the affected arm and hand in unilateral and bilateral everyday tasks. It is comprised of 10 functional tasks such as cutting meat with a knife and fork, donning a t-shirt, and phone use with a score ranging from 0 to a maximum of 5 for each item. The total score is the mean score for all individual item scores.

Outcome measures

Outcome measures
Measure
Interventional Group
n=12 Participants
This is a single group, interventional pilot study. Participants will received 6-week hand training on the HOH device. Subjects will receive arm training 3x/week for 6 weeks
Arm Motor Ability Test (AMAT)
2.35 units on a scale
Standard Deviation 0.58

PRIMARY outcome

Timeframe: Baseline to 6 weeks (discharge)

The Box and Blocks is a performance-based functional assessment of hand dexterity ( gross grasp and release). The total score is the number of 2.5cc blocks successfully transferred from one box to another with the affected hand in one minute.

Outcome measures

Outcome measures
Measure
Interventional Group
n=12 Participants
This is a single group, interventional pilot study. Participants will received 6-week hand training on the HOH device. Subjects will receive arm training 3x/week for 6 weeks
Box and Blocks
6.08 totally number of blocks transferred
Standard Deviation 10

SECONDARY outcome

Timeframe: Baseline to 6 weeks (discharge)

The SULCs is a performance based measure of upper limb capacity after stroke. Each of the 10 items are administered in a hierarchical order and assigned a score of 0 (unable to complete) or 1 (able to complete the task) with a maximum score of 10.

Outcome measures

Outcome measures
Measure
Interventional Group
n=12 Participants
This is a single group, interventional pilot study. Participants will received 6-week hand training on the HOH device. Subjects will receive arm training 3x/week for 6 weeks
Stroke Upper Limb Capacity Scale (SULCS)
5.17 units on a scale
Standard Deviation 2.17

SECONDARY outcome

Timeframe: baseline to 6 weeks (discharge)

A dynamometer measures grip strength in kilograms

Outcome measures

Outcome measures
Measure
Interventional Group
n=12 Participants
This is a single group, interventional pilot study. Participants will received 6-week hand training on the HOH device. Subjects will receive arm training 3x/week for 6 weeks
Hand Dynamometry
8.23 kilograms
Standard Deviation 6.18

SECONDARY outcome

Timeframe: baseline to 6 weeks (discharge)

The Stroke Impact Scale is a stroke-specific questionnaire evaluating quality of life in stroke survivors over eight domains. Each domain is scored independently on an ordinal scale ranging from 0 (minimum) bto a maximum of 5. Only the Hand sub-score was used in this study. Scores for each domain are transformed and range from 0-100. Formula for scoring domains: Transformed Scale = \[(Actual raw score - lowest possible raw score) / Possible raw score\] \* 100

Outcome measures

Outcome measures
Measure
Interventional Group
n=12 Participants
This is a single group, interventional pilot study. Participants will received 6-week hand training on the HOH device. Subjects will receive arm training 3x/week for 6 weeks
Stroke Impact Scale --Hand Sub Scale (SIS-H)
13.33 units on a scale
Standard Deviation 5.48

Adverse Events

Interventional Group

Serious events: 0 serious events
Other events: 7 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Interventional Group
n=12 participants at risk
This is a single group, interventional pilot study. Participants will received 6-week hand training on the HOH device. Subjects will receive arm training 3x/week for 6 weeks
Skin and subcutaneous tissue disorders
mild skin rubbing
58.3%
7/12 • Number of events 7
General disorders
fatigue (cognitive)
25.0%
3/12 • Number of events 3
Musculoskeletal and connective tissue disorders
shoulder fatigue
50.0%
6/12 • Number of events 6

Additional Information

Grace Kim PhD, OTR/L

New York University

Phone: 121-998-5846

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place