University of Michigan Advanced Heart Failure Tele-Monitoring and Flexible Diuretic Project

NCT ID: NCT02344342

Last Updated: 2017-05-02

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-02-28

Study Completion Date

2015-12-31

Brief Summary

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The proposed project is a 2x2 factorial designed study aimed at assessing the impact of 1) a home tele-monitoring system and 2) a flexible diuretic regimen among high risk heart failure patients in the University of Michigan Health System (UMHS).

Detailed Description

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The proposed project is a 2x2 factorial designed study aimed at assessing the impact of 1) a home tele-monitoring system and 2) a flexible diuretic regimen among high risk heart failure patients in the University of Michigan Health System (UMHS). The first intervention consists of the use of a home monitoring tool utilizing a tablet interface. The device facilitates collection of heart failure patient self-care information, including weight, blood pressure, heart rate and heart failure symptoms. This information is collected and stored on a secured server provided by the vendor, and can be viewed by the physician and nursing team. The second intervention is a flexible diuretic regimen strategy. This intervention will be applied in an independent randomized fashion. The flexible regimen will be prescribed by the patient's physician. The two interventions will be applied to heart failure patients treated at the University of Michigan. A total of 400 patients will be enrolled into the study.

Conditions

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Heart Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Health Buddy Web Management system

Patients randomized to the telemonitoring intervention will be assigned to use the Bosch Health Buddy Web management system.

Group Type EXPERIMENTAL

Telemonitoring

Intervention Type DEVICE

The Health Buddy web management system allows the patient to enter self-care data through a study provided tablet computer.

Flexible Diuretic Regimen

Intervention Type OTHER

Patients will have a prescribed diuretic regimen specified by specific weight ranges.

Flexible Diuretic Regimen

Patients randomized into the Flexible Diuretic Regimen intervention will have a diuretic regimen specified by specific weight ranges.

Group Type EXPERIMENTAL

Telemonitoring

Intervention Type DEVICE

The Health Buddy web management system allows the patient to enter self-care data through a study provided tablet computer.

Flexible Diuretic Regimen

Intervention Type OTHER

Patients will have a prescribed diuretic regimen specified by specific weight ranges.

Interventions

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Telemonitoring

The Health Buddy web management system allows the patient to enter self-care data through a study provided tablet computer.

Intervention Type DEVICE

Flexible Diuretic Regimen

Patients will have a prescribed diuretic regimen specified by specific weight ranges.

Intervention Type OTHER

Other Intervention Names

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Bosch Health Buddy Web Management System

Eligibility Criteria

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Inclusion Criteria

1. University of Michigan patients hospitalized for the treatment of heart failure, within the past 30 days.
2. Patients must be receiving an oral loop diuretic on their home regimen or have received intravenous loop diuretic during the index hospitalization at the time of enrollment.
3. Patients must have an assessment of left ventricular function within the previous 2 years.
4. Patients must have LVEF ≤ 40%, or LVEF \>40 with evidence of left atrial enlargement (LA dimension \> 40 mm), BNP \> 200 ng/ml or PCW \> 18 mmHg.

Exclusion Criteria

* Prisoners
* Residents of long term nursing facilities
* Enrollment into a hospice program
* Receiving dialysis
* Patients with dementia
* Patients with dGFR less than 20ml/min.
* Patients being worked up for heart surgery.
* Patients being worked up for heart transplant.
* Patients being evaluated for revascularization.
* Patients being evaluated for heart valve intervention.
* Patients with primary pulmonary hypertension.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Michigan

OTHER

Sponsor Role lead

Responsible Party

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Todd M Koelling, MD

Professor of Internal Medicine, Director of Heart Failure Program

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Todd M Koelling, MD

Role: PRINCIPAL_INVESTIGATOR

University of Michigan

Locations

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University of Michigan Health System

Ann Arbor, Michigan, United States

Site Status

Countries

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United States

Other Identifiers

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HUM00091053

Identifier Type: -

Identifier Source: org_study_id

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