Intra- and Inter-fraction Changes in Radiation Therapy

NCT ID: NCT02344121

Last Updated: 2025-04-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-01-31

Study Completion Date

2028-03-20

Brief Summary

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Analysis to quantify intra-fraction, inter-fraction and post-treatment changes in tumor target volumes and surrounding normal organs in radiation therapy.

Detailed Description

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The accurate and detailed knowledge of the changes (e.g., anatomically/biologically intra- and inter-fraction changes) to be obtained from this study would allow the research team to determine how Adaptive Radiation Therapy (ART) should be performed for a given tumor site/type. Radiation oncologists then can choose a proper ART strategy for a given tumor type to account for the anatomic/biological intra- and inter-fraction changes, improving accuracy of radiation therapy delivery, and in turn reducing treatment related toxicities and/or improving tumor local control.

Conditions

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Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Interventions

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Radiation Therapy

Radiation therapy plans for cancer patients who have completed treatment.

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

°Completed radiation therapy

Exclusion Criteria

°Subjects who refuse voluntary participation
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical College of Wisconsin

OTHER

Sponsor Role lead

Responsible Party

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Eric Paulson

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Eric Paulson, PhD

Role: PRINCIPAL_INVESTIGATOR

Medical College of Wisconsin

Locations

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Froedtert Hospital

Milwaukee, Wisconsin, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Medical College of Wisconsin Cancer Center Clinical Trials Office

Role: CONTACT

414-805-8900

Eric Paulson, PhD

Role: CONTACT

Facility Contacts

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Eric Paulson, PhD

Role: primary

414-805-4400

Other Identifiers

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22316

Identifier Type: -

Identifier Source: org_study_id

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