An Adaptive Strategy for Preventing and Treating Lapses of Retention in Adult HIV Care (AdaPT-R) in Nyanza, Kenya
NCT ID: NCT02338739
Last Updated: 2021-03-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
1816 participants
INTERVENTIONAL
2015-03-31
2020-11-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
HEALTH_SERVICES_RESEARCH
NONE
Study Groups
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REC; Outreach if Failure
REC; Outreach if Failure
Routine education and counseling (REC) services, delivered per Kenya Ministry of Health Guidelines; followed by standard of care (SOC) outreach to encourage return to clinic for patients 14 days late for a scheduled visit in year 1.
REC; SMS + Voucher if Failure
REC; SMS + Voucher if Failure
Routine education and counseling services, delivered per Kenya Ministry of Health (MOH) Guidelines; followed by SMS text messages for patients and reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients 14 days late for a scheduled visit in year 1.
REC; Navigator if Failure
REC; Navigator if Failure
REC services, delivered per Kenya MOH Guidelines; followed by Peer Navigator (tailored outreach and support) for patients 14 days late for a scheduled visit
SMS; Outreach if Failure
SMS; Outreach if Failure
SMS text messages for patients; followed by SOC outreach for patients 14 days late for a scheduled visit
SMS; Outreach if Failure; Stop SMS if Success
SMS; Outreach if Failure; Stop SMS if Success
SMS text messages for patients, followed by SOC outreach for patients 14 days late for a scheduled visit, and discontinuation of SMS text messages if never 14 days late
SMS; SMS+Voucher if Failure
SMS; SMS+Voucher if Failure
SMS text messages for patients, followed by reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients 14 days late for a scheduled visit in year 1.
SMS; SMS+Voucher if Failure; Stop SMS if Success
SMS; SMS+Voucher if Failure; Stop SMS if Success
SMS text messages for patients, followed by reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients 14 days late for a scheduled visit in year 1, and discontinuation of SMS text messages if never 14 days late
SMS; Navigator if Failure
SMS; Navigator if Failure
SMS text messages for patents, followed by Peer Navigator (tailored outreach and support) for patients 14 days late for a scheduled visit
SMS; Navigator if Failure; Stop SMS if Success
SMS; Navigator if Failure; Stop SMS if Success
SMS text messages for patents, followed by Peer Navigator (tailored outreach and support) for patients 14 days late for a scheduled visit, and discontinuation of SMS text messages if never 14 days late
Voucher; Outreach if Failure
Voucher; Outreach if Failure
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by SOC outreach for patients 14 days late for a scheduled visit
Voucher; Outreach if Failure; Stop Voucher if Success
Voucher; Outreach if Failure; Stop Voucher if Success
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by SOC outreach for patients 14 days late for a scheduled visit, and discontinuation of voucher for patients if never 14 days late
Voucher; SMS+Voucher if Failure
Voucher; SMS+Voucher if Failure
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by SMS text message and reimbursement (KSH 400) for transport to the clinic for patients 14 days late for a scheduled visit
Voucher; SMS+Voucher if Failure; Stop Voucher if Success
Voucher; SMS+Voucher if Failure; Stop Voucher if Success
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by SMS text message and reimbursement (KSH 400) for transport to the clinic for patients 14 days late for a scheduled visit, and discontinuation of voucher for patients if never 14 days late
Voucher; Navigator if Failure
Voucher; Navigator if Failure
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by Peer Navigator (tailored outreach and support) for patients 14 days late for a scheduled visit
Voucher; Navigator if Failure; Stop Voucher if Success
Voucher; Navigator if Failure; Stop Voucher if Success
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by Peer Navigator (tailored outreach and support) for patients 14 days late for a scheduled visit, and discontinuation of voucher for patients if never 14 days late
Interventions
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REC; Outreach if Failure
Routine education and counseling (REC) services, delivered per Kenya Ministry of Health Guidelines; followed by standard of care (SOC) outreach to encourage return to clinic for patients 14 days late for a scheduled visit in year 1.
REC; SMS + Voucher if Failure
Routine education and counseling services, delivered per Kenya Ministry of Health (MOH) Guidelines; followed by SMS text messages for patients and reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients 14 days late for a scheduled visit in year 1.
REC; Navigator if Failure
REC services, delivered per Kenya MOH Guidelines; followed by Peer Navigator (tailored outreach and support) for patients 14 days late for a scheduled visit
SMS; Outreach if Failure
SMS text messages for patients; followed by SOC outreach for patients 14 days late for a scheduled visit
SMS; Outreach if Failure; Stop SMS if Success
SMS text messages for patients, followed by SOC outreach for patients 14 days late for a scheduled visit, and discontinuation of SMS text messages if never 14 days late
SMS; SMS+Voucher if Failure
SMS text messages for patients, followed by reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients 14 days late for a scheduled visit in year 1.
SMS; SMS+Voucher if Failure; Stop SMS if Success
SMS text messages for patients, followed by reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients 14 days late for a scheduled visit in year 1, and discontinuation of SMS text messages if never 14 days late
SMS; Navigator if Failure
SMS text messages for patents, followed by Peer Navigator (tailored outreach and support) for patients 14 days late for a scheduled visit
SMS; Navigator if Failure; Stop SMS if Success
SMS text messages for patents, followed by Peer Navigator (tailored outreach and support) for patients 14 days late for a scheduled visit, and discontinuation of SMS text messages if never 14 days late
Voucher; Outreach if Failure
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by SOC outreach for patients 14 days late for a scheduled visit
Voucher; Outreach if Failure; Stop Voucher if Success
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by SOC outreach for patients 14 days late for a scheduled visit, and discontinuation of voucher for patients if never 14 days late
Voucher; SMS+Voucher if Failure
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by SMS text message and reimbursement (KSH 400) for transport to the clinic for patients 14 days late for a scheduled visit
Voucher; SMS+Voucher if Failure; Stop Voucher if Success
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by SMS text message and reimbursement (KSH 400) for transport to the clinic for patients 14 days late for a scheduled visit, and discontinuation of voucher for patients if never 14 days late
Voucher; Navigator if Failure
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by Peer Navigator (tailored outreach and support) for patients 14 days late for a scheduled visit
Voucher; Navigator if Failure; Stop Voucher if Success
Reimbursement at a fixed amount (KSH 400) for transport to the clinic for patients, followed by Peer Navigator (tailored outreach and support) for patients 14 days late for a scheduled visit, and discontinuation of voucher for patients if never 14 days late
Eligibility Criteria
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Inclusion Criteria
* 18 years old
* Planning to remain in the study area (Nyanza region) for the duration of the study, capable of informed consent
* Newly initiating ART (within past 90 days)
* Access to a cell phone
* Ability to read or be read SMS messages
* And willingness to be contacted by clinic upon missed appointment.
Exclusion Criteria
* Hospitalized patients who later recover will be eligible for enrolment at the first post-hospitalization clinic visit during which eligibility criteria are met.
* No access to a cell phone.
* Involvement in studies with the potential to influence retention behaviors.
18 Years
ALL
Yes
Sponsors
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University of California, Berkeley
OTHER
Kenya Medical Research Institute
OTHER
University of Washington
OTHER
National Institute of Mental Health (NIMH)
NIH
University of California, San Francisco
OTHER
Responsible Party
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Principal Investigators
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Elvin Geng, MD
Role: PRINCIPAL_INVESTIGATOR
University of California, San Francisco
Maya Petersen, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
University of California, Berkeley
Locations
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Kenya Medical Research Institute
Kisumu, Nyanza, Kenya
Countries
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References
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Geng EH, Odeny TA, Montoya LM, Iguna S, Kulzer JL, Adhiambo HF, Eshun-Wilson I, Akama E, Nyandieka E, Guze MA, Shade S, Packel L, Fox B, Camlin C, Thirumurthy H, Lyons C, Bukusi EA, Petersen ML. Adaptive Strategies for Retention in Care among Persons Living with HIV. NEJM Evid. 2023 Apr;2(4):10.1056/evidoa2200076. doi: 10.1056/evidoa2200076. Epub 2023 Mar 28.
Other Identifiers
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