Real World Effectiveness of Abatacept in Rheumatoid Arthritis Patients: a Prospective, Single-arm, Open-label, Multi-center Observational Study in Taiwan

NCT ID: NCT02335606

Last Updated: 2022-01-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

213 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-08-06

Study Completion Date

2018-12-31

Brief Summary

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Abatacept Registry in Taiwan

Detailed Description

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Conditions

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Rheumatoid Arthritis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients treating with Abatacept

Patients who are abatacept naive and are initiating abatacept treatment (either IV or SC) including those that are switching from another bDMARD, as well as, patients currently being treated with IV or SC abatacept some of which may have switched from IV abatacept to SC abatacept

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* ≥ 20 years of age
* Who give informed consent
* Confirmed diagnosis of RA (as defined by American College of Rheumatology revised 1987 criteria) and has ≥ 4 of the criteria listed below for ≥6 weeks before study enrollment
* Who self-pay or who are reimbursed by BNHI for abatacept treatment
* With latent TB or who are receiving anti-TB treatment (INH 300 mg, QD) 1 month prior to using abatacept and continuously up to a total of 9 months Willing to follow Taiwan Risk Management Plan guidelines as required by Taiwan health authorities
* Are being treated with abatacept or are abatacept treatment naïve and are initiating abatacept therapy

Exclusion Criteria

* Pregnant or breast feeding
* With active TB
* HBsAg (+)and/or Anti-HCV(+) and/or HBV DNA(+)
* Have cancer (patients who were treated and have no sign of cancer for \> 10 years can be included)
* Are allergic to abatacept
* Enrolled in other RA clinical studies
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bristol-Myers Squibb

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bristol-Myers Squibb

Role: STUDY_DIRECTOR

Bristol-Myers Squibb

Locations

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Local Institution

Taipei, , Taiwan

Site Status

Countries

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Taiwan

Related Links

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Other Identifiers

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IM101-440

Identifier Type: -

Identifier Source: org_study_id

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