Good EULAR Response In Patients With Early Rheumatoid Arthritis

NCT ID: NCT01558089

Last Updated: 2016-11-11

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

76 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-03-31

Study Completion Date

2015-05-31

Brief Summary

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This open-label, prospective, observational study will evaluate the clinical response to etanercept + methotrexate therapy in patients with moderate to severe rheumatoid arthritis, as prescribed by the rheumatologist in a normal clinical setting in Greece

Detailed Description

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All subjects enrolled should meet the usual prescribing criteria for Etanercept as per the local product information and should be entered into the study at the investigator's discretion

Conditions

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Rheumatoid Arthritis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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etanercept + methotrexate

etanercept

Intervention Type DRUG

according to SmPC and clinical practice

methotrexate

Intervention Type DRUG

according to SmPC and clinical practice

Interventions

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etanercept

according to SmPC and clinical practice

Intervention Type DRUG

methotrexate

according to SmPC and clinical practice

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. signed and dated informed consent document
2. 18 years of age and older at the time of consent
3. Patients with moderate-to-severe active rheumatoid arthritis, who satisfy the 2010 Rheumatoid Arthritis Classification Criteria
4. Patients who have been prescribed for first time to receive treatment with MTX + Etanercept prior to enrollment to this study, following routine clinical practice and according to the approved SmPC,
5. Patients with DAS28 ≥ 3.2
6. Duration of disease symptoms ≥ 6 weeks and ≤2 years
7. Failure to respond to prior DMARDs including MTX monotherapy according to routine clinical practice.

Exclusion Criteria

1. Contraindications according to the SmPC
2. History of or present anti-TNFa or other biologic therapy for the treatment of RA
3. Known significant concurrent medical disease according to investigator's opinion and the current SmPC
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pfizer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pfizer CT.gov Call Center

Role: STUDY_DIRECTOR

Pfizer

Locations

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G. Gennimatas General Hospital /Rheumatology Clinic

Athens, Attica, Greece

Site Status

Ippokrateio General Hospital of Athens / 2nd internal Medicine Clinic of the University of Athens

Athens, Attica, Greece

Site Status

University General Hospital of Heraklion

Heraklion, Creete, Greece

Site Status

G. Papanikolaoy

Thessaloniki, Exochi, Greece

Site Status

424 Military Hospital

Thessaloniki, Thessalonikis, Greece

Site Status

Euromedica Kyanous Stavros

Thessaloniki, Thessaloniki, Greece

Site Status

Laiko General Peripheral Hospital

Athens, , Greece

Site Status

Peripheral University General Hospital of Larissa

Larissa, , Greece

Site Status

"Olympion therapeutic center" General Clinic of Patras

Pátrai, , Greece

Site Status

Countries

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Greece

Related Links

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Other Identifiers

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B1801138

Identifier Type: -

Identifier Source: org_study_id