Trial Outcomes & Findings for Optimizing Behavioral Health Homes for Adults With Serious Mental Illness (NCT NCT02318797)

NCT ID: NCT02318797

Last Updated: 2018-02-22

Results Overview

Assessed using the PAM, a 13-item scale that renders a total activation score. This measure gauges the knowledge, skills, and confidence of patients essential to managing their own health and health care. It divides into progressively higher levels of activation: starting to take a role, building knowledge and confidences, taking action, and maintaining behaviors. The raw score scale for the PAM ranges from 13 to 52. The activation scale for the PAM ranges from 0 to 100. The lower values represent a poor outcome while higher values represent a better outcome.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

1229 participants

Primary outcome timeframe

Baseline and every 6 months over 2 year active intervention period

Results posted on

2018-02-22

Participant Flow

Participant milestones

Participant milestones
Measure
Provider-Supported Integrated Care
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Patient Self-Directed Care
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Overall Study
STARTED
713
516
Overall Study
COMPLETED
611
428
Overall Study
NOT COMPLETED
102
88

Reasons for withdrawal

Reasons for withdrawal
Measure
Provider-Supported Integrated Care
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Patient Self-Directed Care
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Overall Study
Death
6
3
Overall Study
Lost to Follow-up
96
85

Baseline Characteristics

Optimizing Behavioral Health Homes for Adults With Serious Mental Illness

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Patient Self-Directed Care
n=516 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=713 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Total
n=1229 Participants
Total of all reporting groups
Age, Continuous
42.37 years
n=93 Participants
43.47 years
n=4 Participants
43.01 years
n=27 Participants
Sex: Female, Male
Female
341 Participants
n=93 Participants
428 Participants
n=4 Participants
769 Participants
n=27 Participants
Sex: Female, Male
Male
175 Participants
n=93 Participants
285 Participants
n=4 Participants
460 Participants
n=27 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
2 Participants
n=93 Participants
4 Participants
n=4 Participants
6 Participants
n=27 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
514 Participants
n=93 Participants
709 Participants
n=4 Participants
1223 Participants
n=27 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=93 Participants
0 Participants
n=4 Participants
0 Participants
n=27 Participants
Race (NIH/OMB)
American Indian or Alaska Native
1 Participants
n=93 Participants
2 Participants
n=4 Participants
3 Participants
n=27 Participants
Race (NIH/OMB)
Asian
0 Participants
n=93 Participants
3 Participants
n=4 Participants
3 Participants
n=27 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=93 Participants
0 Participants
n=4 Participants
0 Participants
n=27 Participants
Race (NIH/OMB)
Black or African American
21 Participants
n=93 Participants
72 Participants
n=4 Participants
93 Participants
n=27 Participants
Race (NIH/OMB)
White
483 Participants
n=93 Participants
621 Participants
n=4 Participants
1104 Participants
n=27 Participants
Race (NIH/OMB)
More than one race
11 Participants
n=93 Participants
15 Participants
n=4 Participants
26 Participants
n=27 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=93 Participants
0 Participants
n=4 Participants
0 Participants
n=27 Participants

PRIMARY outcome

Timeframe: Baseline and every 6 months over 2 year active intervention period

Population: Includes those who completed the measure at baseline and whose measure was able to be scored (ie. was not missing data which would have rendered it unusable in analysis)

Assessed using the PAM, a 13-item scale that renders a total activation score. This measure gauges the knowledge, skills, and confidence of patients essential to managing their own health and health care. It divides into progressively higher levels of activation: starting to take a role, building knowledge and confidences, taking action, and maintaining behaviors. The raw score scale for the PAM ranges from 13 to 52. The activation scale for the PAM ranges from 0 to 100. The lower values represent a poor outcome while higher values represent a better outcome.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=438 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=615 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Patient Activation in Care (PAM, a 13-item Scale)
6-month follow up
56.84 units on a scale
Standard Deviation 14.45
58.74 units on a scale
Standard Deviation 14.90
Change in Patient Activation in Care (PAM, a 13-item Scale)
Baseline
56.99 units on a scale
Standard Deviation 15.03
56.77 units on a scale
Standard Deviation 14.59
Change in Patient Activation in Care (PAM, a 13-item Scale)
12-month follow up
58.36 units on a scale
Standard Deviation 15.08
57.46 units on a scale
Standard Deviation 14.89
Change in Patient Activation in Care (PAM, a 13-item Scale)
18-month follow up
58.90 units on a scale
Standard Deviation 14.98
57.84 units on a scale
Standard Deviation 15.11
Change in Patient Activation in Care (PAM, a 13-item Scale)
24-month follow up
57.04 units on a scale
Standard Deviation 15.15
58.61 units on a scale
Standard Deviation 15.64

PRIMARY outcome

Timeframe: Baseline and every 6 months over 2 year active intervention period

Population: Includes those who completed the measure at baseline and whose measure was able to be scored (ie. was not missing data which would have rendered it unusable in analysis)

Health status is measured using the SF-12v2™, a widely used and practical health survey tool consisting of 12 questions and two sub-scales for measuring physical and mental health status and symptom effects and functioning. The physical health component summary score is created using a weighted sum of all 12 items and then a scoring algorithm places negative weights on four of the health domains and positive weights on the other four health domains. Scores range from 0-100 and better physical health is indicated by a higher score.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=511 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=705 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Health Status ( SF-12v2™): Physical Health Sub-scale
18-month follow up
39.71 units on a scale
Standard Deviation 11.80
41.28 units on a scale
Standard Deviation 10.99
Change in Health Status ( SF-12v2™): Physical Health Sub-scale
Baseline
42.12 units on a scale
Standard Deviation 11.47
42.47 units on a scale
Standard Deviation 11.05
Change in Health Status ( SF-12v2™): Physical Health Sub-scale
6-month follow up
41.19 units on a scale
Standard Deviation 11.44
42.26 units on a scale
Standard Deviation 11.00
Change in Health Status ( SF-12v2™): Physical Health Sub-scale
12-month follow up
41.33 units on a scale
Standard Deviation 10.78
41.19 units on a scale
Standard Deviation 11.32
Change in Health Status ( SF-12v2™): Physical Health Sub-scale
24-month follow up
40.07 units on a scale
Standard Deviation 12.16
41.96 units on a scale
Standard Deviation 10.99

PRIMARY outcome

Timeframe: Updated annually using claims data over 2 year active intervention period

Population: Study participants who were Medicaid eligible for 80% of the year prior to the data collection time point

The frequency of primary/specialty care visits over two 12-month time periods.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=449 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=648 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Engagement in Primary/Specialty Care
Baseline
9.87 Frequency of visits in 12-month periods
Standard Deviation 7.93
8.72 Frequency of visits in 12-month periods
Standard Deviation 6.69
Change in Engagement in Primary/Specialty Care
12-month follow up
11.33 Frequency of visits in 12-month periods
Standard Deviation 8.46
11.77 Frequency of visits in 12-month periods
Standard Deviation 7.93
Change in Engagement in Primary/Specialty Care
24-month follow up
11.05 Frequency of visits in 12-month periods
Standard Deviation 8.58
10.88 Frequency of visits in 12-month periods
Standard Deviation 7.90

PRIMARY outcome

Timeframe: Baseline and every 6 months during the active intervention period

Population: Includes those who completed the measure at baseline and whose measure was able to be scored (ie. was not missing data which would have rendered it unusable in analysis)

Health status is measured using the SF-12v2™, a widely used and practical health survey tool consisting of 12 questions and two sub-scales for measuring physical and mental health status and symptom effects and functioning. The mental health component summary score is created using a weighted sum of all 12 items and then a scoring algorithm places negative weights on four of the health domains and positive weights on the other four health domains (reverse of the weighting used for the physical health component summary score). Scores range from 0-100 and better mental health is indicated by a higher score.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=510 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=703 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Health Status ( SF-12v2™): Mental Health Sub-scale
Baseline
36.59 units on a scale
Standard Deviation 11.91
39.57 units on a scale
Standard Deviation 12.13
Change in Health Status ( SF-12v2™): Mental Health Sub-scale
6-month follow up
37.79 units on a scale
Standard Deviation 11.18
40.78 units on a scale
Standard Deviation 12.02
Change in Health Status ( SF-12v2™): Mental Health Sub-scale
12-month follow up
39.42 units on a scale
Standard Deviation 10.35
39.80 units on a scale
Standard Deviation 11.48
Change in Health Status ( SF-12v2™): Mental Health Sub-scale
18-month follow up
38.52 units on a scale
Standard Deviation 11.15
40.63 units on a scale
Standard Deviation 11.40
Change in Health Status ( SF-12v2™): Mental Health Sub-scale
24-month follow up
39.63 units on a scale
Standard Deviation 11.38
40.56 units on a scale
Standard Deviation 11.92

SECONDARY outcome

Timeframe: Baseline and every 6 months during the active intervention period

Population: Includes those who completed the measure at baseline and whose measure was able to be scored (ie. was not missing data which would have rendered it unusable in analysis)

Assessed using the Hope Scale, an instrument designed to measure hope that has been previously used in health services research. Twelve items are rated on a four-point response scale ranging from "definitely false" to "definitely true" and summed to produce a total score. The hope scale ranges from 1 to 10, with 1 being no hope and 10 being filled with hope.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=510 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=710 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Hope (Hope Scale)
Baseline
6.24 Units on a scale
Standard Deviation 2.59
6.46 Units on a scale
Standard Deviation 2.62
Change in Hope (Hope Scale)
6 month follow-up
6.24 Units on a scale
Standard Deviation 2.52
6.57 Units on a scale
Standard Deviation 2.60
Change in Hope (Hope Scale)
12 month follow-up
6.47 Units on a scale
Standard Deviation 2.47
6.56 Units on a scale
Standard Deviation 2.64
Change in Hope (Hope Scale)
18 month follow-up
6.31 Units on a scale
Standard Deviation 2.47
6.65 Units on a scale
Standard Deviation 2.53
Change in Hope (Hope Scale)
24 month follow-up
6.35 Units on a scale
Standard Deviation 2.47
6.51 Units on a scale
Standard Deviation 2.61

SECONDARY outcome

Timeframe: Baseline and every 6 months over 2 year active intervention period

Population: Includes those who completed the measure at baseline and whose measure was able to be scored (ie. was not missing data which would have rendered it unusable in analysis)

Patient quality of life is measured using the QLESQ (Quality of Life Enjoyment and Satisfaction Questionnaire) in which participants respond on a scale of 1 (very poor) to 5 (very good) their level of satisfaction with a variety of social and physical domains. The total raw score ranges from 14 to 70 or 0-100%. Only the first 14 items yield the raw total score as the last two items are standalone. The raw total score is transformed into a percentage maximum possible score using the following formula: (raw total score-minimum score)/(maximum possible raw score-minimum score). The lower values/percentages represent a poor outcome while higher values/percentages represent a better outcome. The information below reflects raw scores (rather than percentages).

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=426 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=638 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Quality of Life (QLESQ)
12 month follow-up
44.52 Units on a scale
Standard Deviation 10.36
44.35 Units on a scale
Standard Deviation 11.42
Change in Quality of Life (QLESQ)
18 month follow-up
43.10 Units on a scale
Standard Deviation 10.75
44.88 Units on a scale
Standard Deviation 11.34
Change in Quality of Life (QLESQ)
24 month follow-up
43.98 Units on a scale
Standard Deviation 11.65
45.80 Units on a scale
Standard Deviation 12.02
Change in Quality of Life (QLESQ)
Baseline
42.00 Units on a scale
Standard Deviation 11.60
44.38 Units on a scale
Standard Deviation 11.12
Change in Quality of Life (QLESQ)
6 month follow-up
42.29 Units on a scale
Standard Deviation 11.32
45.76 Units on a scale
Standard Deviation 11.09

SECONDARY outcome

Timeframe: Updated annually using claims data over 2 year active intervention period

Population: The N for the time point with the greatest # of participants who were prescribed a diabetes medication.

Claims data used to calculate diabetes medication possession ratio (MPO) for participants diagnosed with diabetes in 6 month time periods. If the (first\_fill - last\_end\_Date) \> 180 then MPR = (total days supply - (first\_fill - last\_end\_Date) - 180 ) / 180. If the total duration was not greater than 180 days, MPR = total days supply / 180.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=47 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=58 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Medication Adherence - Diabetes
6 month follow-up
0.86 Medication possession ratio
Standard Deviation 0.27
0.91 Medication possession ratio
Standard Deviation 0.20
Change in Medication Adherence - Diabetes
12 month follow-up
0.83 Medication possession ratio
Standard Deviation 0.27
0.91 Medication possession ratio
Standard Deviation 0.17
Change in Medication Adherence - Diabetes
18 month follow-up
0.86 Medication possession ratio
Standard Deviation 0.23
0.88 Medication possession ratio
Standard Deviation 0.24
Change in Medication Adherence - Diabetes
24 month follow-up
0.77 Medication possession ratio
Standard Deviation 0.32
0.91 Medication possession ratio
Standard Deviation 0.17
Change in Medication Adherence - Diabetes
Baseline
0.78 Medication possession ratio
Standard Deviation 0.30
0.89 Medication possession ratio
Standard Deviation 0.20

SECONDARY outcome

Timeframe: Baseline and every 6 months over 2 year active intervention period

Population: Includes those who completed the measure at baseline and whose measure was able to be scored (ie. was not missing data which would have rendered it unusable in analysis)

Functional status is measured using the Sheehan Disability Scale which assesses functional impairment in three domains including: work/school, social and family life. Respondents rate the extent to which work/school, social life and home life or family responsibilities are impaired by symptoms. The three items from the Sheehan Disability Scale are summed together into a single measure of global functional impairment. This measure ranges from 0 to 30, with 0 being unimpaired and 30 being highly impaired.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=473 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=686 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Functional Status (Sheehan Disability Scale)
Baseline
13.82 Units on a scale
Standard Deviation 9.20
12.71 Units on a scale
Standard Deviation 8.82
Change in Functional Status (Sheehan Disability Scale)
6 month follow-up
12.97 Units on a scale
Standard Deviation 8.87
11.33 Units on a scale
Standard Deviation 8.53
Change in Functional Status (Sheehan Disability Scale)
12 month follow-up
12.71 Units on a scale
Standard Deviation 8.60
12.29 Units on a scale
Standard Deviation 8.62
Change in Functional Status (Sheehan Disability Scale)
18 month follow-up
13.58 Units on a scale
Standard Deviation 8.57
12.20 Units on a scale
Standard Deviation 8.54
Change in Functional Status (Sheehan Disability Scale)
24 month follow-up
13.31 Units on a scale
Standard Deviation 8.69
11.90 Units on a scale
Standard Deviation 8.58

SECONDARY outcome

Timeframe: Updated annually using claims data over 2 year active intervention period

Population: \# of individuals with 80% Medicaid eligibility in the 12 months prior to the data collection time point.

Behavioral and physical health claims data will be obtained to determine frequency of emergent service use for participants over 12-month time periods.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=449 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=648 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Emergent Care Use (Claims Data)
Baseline
3.83 frequency of visits in 12-month periods
Standard Deviation 5.87
2.36 frequency of visits in 12-month periods
Standard Deviation 4.32
Change in Emergent Care Use (Claims Data)
12-month follow up
3.21 frequency of visits in 12-month periods
Standard Deviation 5.07
2.37 frequency of visits in 12-month periods
Standard Deviation 4.63
Change in Emergent Care Use (Claims Data)
24-month follow-up
2.68 frequency of visits in 12-month periods
Standard Deviation 4.44
2.19 frequency of visits in 12-month periods
Standard Deviation 4.08

SECONDARY outcome

Timeframe: Updated annually using claims data over 2 year active intervention period

Population: Study participants who were Medicaid eligible for 80% of the year prior to the data collection time point

Frequency of lab tests (glucose, lipids, EKG) in 12 month periods

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=449 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=648 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Lab Monitoring - Overall
24 month follow-up
1.52 frequency of lab tests in 12 mo. period
Standard Deviation 2.36
1.30 frequency of lab tests in 12 mo. period
Standard Deviation 2.70
Change in Lab Monitoring - Overall
Baseline
1.67 frequency of lab tests in 12 mo. period
Standard Deviation 2.64
1.37 frequency of lab tests in 12 mo. period
Standard Deviation 2.65
Change in Lab Monitoring - Overall
12 month follow-up
1.60 frequency of lab tests in 12 mo. period
Standard Deviation 2.79
1.49 frequency of lab tests in 12 mo. period
Standard Deviation 2.79

SECONDARY outcome

Timeframe: Baseline and every 6 months over 2 year active intervention period

Population: Includes those who completed the measure at baseline and whose measure was able to be scored (ie. was not missing data which would have rendered it unusable in analysis)

Change in patient satisfaction with care was assessed using the Patient Assessment of Care for Chronic Conditions (PACIC). Each item of the PACIC is on a 1 to 5 scale. The total score is the average of all 20 item scores. Higher scores represent increased frequency of structured chronic care.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=444 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=647 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Patient Satisfaction With Care
12 month follow-up
3.25 Units on a scale
Standard Deviation 0.99
3.31 Units on a scale
Standard Deviation 0.95
Change in Patient Satisfaction With Care
Baseline
2.99 Units on a scale
Standard Deviation 1.06
3.17 Units on a scale
Standard Deviation 0.96
Change in Patient Satisfaction With Care
6 month follow-up
3.17 Units on a scale
Standard Deviation 1.04
3.23 Units on a scale
Standard Deviation 0.95
Change in Patient Satisfaction With Care
18 month follow-up
3.16 Units on a scale
Standard Deviation 1.03
3.25 Units on a scale
Standard Deviation 0.95
Change in Patient Satisfaction With Care
24 month follow-up
3.17 Units on a scale
Standard Deviation 1.10
3.37 Units on a scale
Standard Deviation 0.95

SECONDARY outcome

Timeframe: Updated annually using claims data over 2 year active intervention period

Population: The N for the time point with the greatest # of participants who were prescribed a antipsychotic medication.

Claims data used to calculate antipsychotic medication possession ratio (MPR) for participants in 6 month time periods. If the (first\_fill - last\_end\_Date) \> 180 then MPR = (total days supply - (first\_fill - last\_end\_Date) - 180 ) / 180. If the total duration was not greater than 180 days, MPR = total days supply / 180.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=151 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=198 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Medication Adherence - Antipsychotics
Baseline
0.73 Medication possession ratio
Standard Deviation 0.29
0.81 Medication possession ratio
Standard Deviation 0.26
Change in Medication Adherence - Antipsychotics
6 month follow-up
0.70 Medication possession ratio
Standard Deviation 0.32
0.80 Medication possession ratio
Standard Deviation 0.27
Change in Medication Adherence - Antipsychotics
12 month follow-up
0.74 Medication possession ratio
Standard Deviation 0.32
0.82 Medication possession ratio
Standard Deviation 0.27
Change in Medication Adherence - Antipsychotics
18 month follow-up
0.78 Medication possession ratio
Standard Deviation 0.26
0.78 Medication possession ratio
Standard Deviation 0.28
Change in Medication Adherence - Antipsychotics
24 month follow-up
0.78 Medication possession ratio
Standard Deviation 0.28
0.81 Medication possession ratio
Standard Deviation 0.27

SECONDARY outcome

Timeframe: Updated annually using claims data over 2 year active intervention period

Population: The N for the time point with the greatest # of participants who were prescribed a antihypertensive medication.

Claims data used to calculate antihypertensive medication possession ratio (MPR) for participants in 6 month time periods. If the (first\_fill - last\_end\_Date) \> 180 then MPR = (total days supply - (first\_fill - last\_end\_Date) - 180 ) / 180. If the total duration was not greater than 180 days, MPR = total days supply / 180.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=98 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=126 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Medication Adherence - Hypertension
Baseline
0.75 Medication possession ratio
Standard Deviation 0.31
0.76 Medication possession ratio
Standard Deviation 0.30
Change in Medication Adherence - Hypertension
6 month follow-up
0.73 Medication possession ratio
Standard Deviation 0.31
0.79 Medication possession ratio
Standard Deviation 0.30
Change in Medication Adherence - Hypertension
12 month follow-up
0.76 Medication possession ratio
Standard Deviation 0.29
0.82 Medication possession ratio
Standard Deviation 0.27
Change in Medication Adherence - Hypertension
18 month follow-up
0.81 Medication possession ratio
Standard Deviation 0.28
0.80 Medication possession ratio
Standard Deviation 0.28
Change in Medication Adherence - Hypertension
24 month follow-up
0.83 Medication possession ratio
Standard Deviation 0.30
0.82 Medication possession ratio
Standard Deviation 0.27

SECONDARY outcome

Timeframe: Updated annually using claims data over 2 year active intervention period

Population: The N for the time point with the greatest # of participants who were prescribed am antidepressant medication.

Claims data used to calculate antidepressant medication possession ratio (MPR) for participants in 6 month time periods. If the (first\_fill - last\_end\_Date) \> 180 then MPR = (total days supply - (first\_fill - last\_end\_Date) - 180 ) / 180. If the total duration was not greater than 180 days, MPR = total days supply / 180.

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=188 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=231 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Medication Adherence - Antidepressants
24 month follow-up
0.83 Medication possession ratio
Standard Deviation 0.27
0.82 Medication possession ratio
Standard Deviation 0.26
Change in Medication Adherence - Antidepressants
Baseline
0.79 Medication possession ratio
Standard Deviation 0.31
0.84 Medication possession ratio
Standard Deviation 0.27
Change in Medication Adherence - Antidepressants
6 month follow-up
0.79 Medication possession ratio
Standard Deviation 0.29
0.86 Medication possession ratio
Standard Deviation 0.24
Change in Medication Adherence - Antidepressants
12 month follow-up
0.81 Medication possession ratio
Standard Deviation 0.27
0.84 Medication possession ratio
Standard Deviation 0.27
Change in Medication Adherence - Antidepressants
18 month follow-up
0.81 Medication possession ratio
Standard Deviation 0.29
0.82 Medication possession ratio
Standard Deviation 0.27

SECONDARY outcome

Timeframe: Updated annually using claims data over 2 year active intervention period

Population: Study participants who were Medicaid eligible for 80% of the year prior to the data collection time point

Frequency of glucose lab tests in 12 month periods

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=449 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=648 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Lab Monitoring - Glucose
Baseline
1.55 frequency of lab tests in 12 mo. period
Standard Deviation 2.55
1.21 frequency of lab tests in 12 mo. period
Standard Deviation 2.52
Change in Lab Monitoring - Glucose
12 month follow-up
1.46 frequency of lab tests in 12 mo. period
Standard Deviation 2.69
1.33 frequency of lab tests in 12 mo. period
Standard Deviation 2.65
Change in Lab Monitoring - Glucose
24 month follow-up
1.41 frequency of lab tests in 12 mo. period
Standard Deviation 2.31
1.16 frequency of lab tests in 12 mo. period
Standard Deviation 2.50

SECONDARY outcome

Timeframe: Updated annually using claims data over 2 year active intervention period

Population: Study participants who were Medicaid eligible for 80% of the year prior to the data collection time point

Frequency of lipid lab tests in 12 month periods

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=449 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=648 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Lab Monitoring - Lipids
Baseline
0.37 frequency of lab tests in 12 mo. period
Standard Deviation 0.74
0.41 frequency of lab tests in 12 mo. period
Standard Deviation 0.86
Change in Lab Monitoring - Lipids
12 month follow-up
0.35 frequency of lab tests in 12 mo. period
Standard Deviation 0.73
0.46 frequency of lab tests in 12 mo. period
Standard Deviation 0.90
Change in Lab Monitoring - Lipids
24 month follow-up
0.40 frequency of lab tests in 12 mo. period
Standard Deviation 0.73
0.46 frequency of lab tests in 12 mo. period
Standard Deviation 1.39

SECONDARY outcome

Timeframe: Updated annually using claims data over 2 year active intervention period

Population: Study participants who were Medicaid eligible for 80% of the year prior to the data collection time point

Frequency of EKG tests in 12 month periods

Outcome measures

Outcome measures
Measure
Patient Self-Directed Care
n=449 Participants
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=648 Participants
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
Change in Lab Monitoring - EKG
Baseline
0.12 frequency of EKG tests in 12 mo. period
Standard Deviation 0.39
0.15 frequency of EKG tests in 12 mo. period
Standard Deviation 0.51
Change in Lab Monitoring - EKG
12 month follow-up
0.13 frequency of EKG tests in 12 mo. period
Standard Deviation 0.43
0.16 frequency of EKG tests in 12 mo. period
Standard Deviation 0.49
Change in Lab Monitoring - EKG
24 month follow-up
0.10 frequency of EKG tests in 12 mo. period
Standard Deviation 0.34
0.12 frequency of EKG tests in 12 mo. period
Standard Deviation 0.42

Adverse Events

Patient Self-Directed Care

Serious events: 3 serious events
Other events: 0 other events
Deaths: 3 deaths

Provider-Supported Integrated Care

Serious events: 6 serious events
Other events: 0 other events
Deaths: 6 deaths

Serious adverse events

Serious adverse events
Measure
Patient Self-Directed Care
n=516 participants at risk
See intervention description Patient Self-Directed Care: Patient self-management toolkits, web portal with information on health conditions, personal health care use data, health tracking tools and wellness programs
Provider-Supported Integrated Care
n=713 participants at risk
See intervention description Provider-Supported Integrated Care: Registered nurse on staff at community mental health centers with access to patient-level physical health information to: 1) work with patients on coordinating their care, 2) enhance communication between providers and payer, and 3) provide patient wellness support and education
General disorders
Death - not associated with study activities
0.58%
3/516 • Number of events 3 • Over the entire 2 year implementation and data collection period: October 2013 - January 2016
0.84%
6/713 • Number of events 6 • Over the entire 2 year implementation and data collection period: October 2013 - January 2016

Other adverse events

Adverse event data not reported

Additional Information

Charles Reynolds, MD

University of Pittsburgh Department of Psychiatry

Phone: 412-246-6414

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place