Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis
NCT ID: NCT02315729
Last Updated: 2023-09-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
380 participants
OBSERVATIONAL
2016-11-30
2028-12-31
Brief Summary
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The investigators hypothesize that alterations in specific genetic markers will be correlated with the progression of AIS curves over time. Thus, these markers could be used in the future to develop a reliable, inexpensive and relatively non-invasive cell based diagnostic test to (1) predict spinal curve progression in AIS, (2) select patients likely to benefit from early surgical intervention, and (3) potentially screen for asymptomatic children at risk of developing idiopathic scoliosis.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Diagnosed with mild-moderate spine deformity (Cobb angle 15-30 degrees)
Exclusion Criteria
* Trauma
* Inflammatory disease
* Malignancies
* Diabetes
* History of previous spine surgery
10 Years
13 Years
FEMALE
No
Sponsors
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University of Colorado, Denver
OTHER
Responsible Party
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Principal Investigators
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Evalina L Burger, MD
Role: PRINCIPAL_INVESTIGATOR
University of Colorado, Denver
Locations
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Children'S Hospital of Colorado
Denver, Colorado, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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14-0884
Identifier Type: -
Identifier Source: org_study_id
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