Toxicity Attributed to Genetic Polymorphisms in Testicular Germ Cell Tumor Survivors

NCT ID: NCT02303015

Last Updated: 2023-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

430 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-08-31

Study Completion Date

2023-06-30

Brief Summary

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The purpose of this study is to identify genetic variations in survivors of testicular cancer and connect these variations to differences in risks of late effects.

Detailed Description

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Identification of late-effects through questionnaires and linkage to national registries. DNA samples will be gathered through buccal swabs or saliva kits and analysed with whole exome-sequencing.

Conditions

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Germ Cell Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Danish germ cell cancer patients

Danish patients with germ cell cancer diagnosed from 1984 to 2007.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Danish citizen
* Diagnosed with germ cell cancer from 1984 to 2007
* Treated initially at a Danish hospital
* Treated with standard treatment regimens.

Exclusion Criteria

* Treated initially at a foreign hospital
Minimum Eligible Age

15 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Gedske Daugaard

Professor M.D. DMSc

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gedske Daugaard, MD DMSc

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet, Denmark

Locations

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Dept. of Oncology, Rigshospitalet

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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DaTeCa01

Identifier Type: -

Identifier Source: org_study_id

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