Trial Outcomes & Findings for Q-collar and Brain Injury Biomarkers (NCT NCT02271451)

NCT ID: NCT02271451

Last Updated: 2020-09-04

Results Overview

measured white matter changes, mean diffusivity (MD), and radial diffusivity (RD)

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

15 participants

Primary outcome timeframe

2 years

Results posted on

2020-09-04

Participant Flow

Participant milestones

Participant milestones
Measure
Q Collar
subjects wearing the q collar Q collar: collar worn around neck
Control
subjects not wearing the Q collar
Overall Study
STARTED
7
8
Overall Study
COMPLETED
7
7
Overall Study
NOT COMPLETED
0
1

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Q-collar and Brain Injury Biomarkers

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Q Collar
n=7 Participants
subjects wearing the q collar Q collar: collar worn around neck
Control
n=8 Participants
subjects not wearing the Q collar
Total
n=15 Participants
Total of all reporting groups
Age, Categorical
<=18 years
7 Participants
n=5 Participants
8 Participants
n=7 Participants
15 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Sex: Female, Male
Female
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Sex: Female, Male
Male
7 Participants
n=5 Participants
8 Participants
n=7 Participants
15 Participants
n=5 Participants
Region of Enrollment
United States
7 participants
n=5 Participants
8 participants
n=7 Participants
15 participants
n=5 Participants

PRIMARY outcome

Timeframe: 2 years

Population: Changes seen on DTI imaging

measured white matter changes, mean diffusivity (MD), and radial diffusivity (RD)

Outcome measures

Outcome measures
Measure
Q Collar
n=7 Participants
subjects wearing the q collar Q collar: collar worn around neck
Control
n=7 Participants
subjects not wearing the Q collar
Longitudinal DTI Changes
Baseline MD
0.000809 voxels
Standard Deviation 0.000056
0.000760 voxels
Standard Deviation 0.000089
Longitudinal DTI Changes
Mid-Season MD
0.000763 voxels
Standard Deviation 0.000072
0.000843 voxels
Standard Deviation 0.000062
Longitudinal DTI Changes
Baseline RD
0.000525 voxels
Standard Deviation 0.000044
0.000426 voxels
Standard Deviation 0.000062
Longitudinal DTI Changes
Mid-Season RD
0.000447 voxels
Standard Deviation 0.000062
0.000511 voxels
Standard Deviation 0.000037

Adverse Events

Q Collar

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Gregory Myer

Cincinnati Children's Hospital

Phone: 513-636-4366

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place