A Prospective Longitudinal Breast Cancer Study

NCT ID: NCT02270931

Last Updated: 2021-08-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

130 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-05-31

Study Completion Date

2021-06-30

Brief Summary

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The purpose of this study is to obtain sufficient specimens and correlating clinical data from a well-controlled prospective clinical trial collecting longitudinal specimens from subjects diagnosed with any stage of breast cancer.

Detailed Description

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The study objectives are described below:

1. Obtain serum and plasma specimens longitudinally collected from a minimum of 130 subjects diagnosed with breast cancer and are about to or are currently undergoing treatment and follow-up. Specimens will be used to evaluate CA 15-3 assays, currently under development, as an aid for monitoring recurrence or progressive disease.
2. To store any remaining specimens for use in future cancer research and to evaluate as yet undetermined biomarkers for the development of IVDs, including additional CA 15-3 assays, for monitoring the course of disease and therapy in subjects diagnosed with breast cancer.

Conditions

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Breast Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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CA 15-3 Assay

Physicians use the CA 15-3 test result to manage their patients

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Males and females, age≥ 18 years
* Histologic/pathologic confirmation of breast cancer
* Any stage of disease: Newly diagnosed, stable, disease progression, surveillance
* Any treatment time point: Treatment naïve, currently receiving or completed therapy for breast cancer including active monitoring.
* Individuals with a history of malignant disease other than breast cancer that was resected greater than 5 years ago and are currently in remission are eligible.
* Able to understand and willing to provide informed consent

Exclusion Criteria

* Males and females, age \<18 years
* No histologic/pathologic confirmation of breast cancer
* Any concurrent malignancy other than basal or squamous cell skin cancers, in-situ cervical cancer, or breast cancer.
* Treatment plan with fewer than three visits expected in 3 years' time
* Unable to provide informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fujirebio Diagnostics, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Diana Dickson

Role: STUDY_DIRECTOR

Fujirebio Diagnostics, Inc.

Locations

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Jane Skelton, MD

Boca Raton, Florida, United States

Site Status

Broward Health Medical Center

Fort Lauderdale, Florida, United States

Site Status

New Hanover Regional Medical Center

Wilmington, North Carolina, United States

Site Status

Countries

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United States

Other Identifiers

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FDI-69

Identifier Type: -

Identifier Source: org_study_id

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