Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease

NCT ID: NCT02244853

Last Updated: 2014-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

51703 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-09-30

Study Completion Date

2014-12-31

Brief Summary

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The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study. CALIBER links patient records from four different data sources: Clinical Practice Research Database (CPRD), MINAP (Myocardial Ischaemia National Audit Project registry) Hospital Episodes Statistics (HES), the Office for National Statistics (ONS).

Detailed Description

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This study is part of the CALIBER (Cardiovascular disease research using linked bespoke studies and electronic records) programme funded over 5 years from the NIHR and Wellcome Trust. The central theme of the CALIBER research is linkage of the Myocardial Ischaemia National Audit Project (MINAP) with primary care (GPRD) and other resources. The overarching aim of CALIBER is to better understand the aetiology and prognosis of specific coronary phenotypes across a range of causal domains, particularly where electronic records provide a contribution beyond traditional studies. CALIBER has received both Ethics approval (ref 09/H0810/16) and ECC approval (ref ECC 2-06(b)/2009 CALIBER dataset).

Conditions

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Stable Angina Myocardial Infarction Coronary Heart Disease Heart Failure Stroke Death, Sudden, Cardiac Peripheral Arterial Disease Atrial Fibrillation Bleeding

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Aged \>=30 years at study entry -\>=1 year registration prior to the 'index date'

Exclusion Criteria

* Free from previous atherosclerotic events
* No heart rate measurement after their 'index date' of eligibility to entry the study
Eligible Sex

Accepts Healthy Volunteers

Yes

Sponsors

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Wellcome Trust

OTHER

Sponsor Role collaborator

National Institute for Health Research, United Kingdom

OTHER_GOV

Sponsor Role collaborator

University College, London

OTHER

Sponsor Role lead

Responsible Party

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Harry Hemingway

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Harry Hemingway, Professor

Role: STUDY_DIRECTOR

Farr Institute

Locations

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Farr Institute, University College London

London, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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086091/Z/08/Z

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

RP-PG-0407-10314

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

12_153R_IP24

Identifier Type: -

Identifier Source: org_study_id

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