PLATINUM Diversity

NCT ID: NCT02240810

Last Updated: 2019-05-15

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

1501 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-10-31

Study Completion Date

2016-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To compile acute procedural performance and clinical outcomes data for the Promus PREMIER everolimus-eluting coronary stent system in understudied/underserved patient populations including women and minorities.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Atherosclerosis Coronary Artery Disease

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

PLATINUM Diversity (Overall)

PLATINUM Diversity (Overall) population. Test device is Promus PREMIER Everolimus-Eluting Platinum Chromium Coronary Stent System (CSS)

Percutaneous coronary intervention (Promus PREMIER)

Intervention Type DEVICE

Interventional coronary artery stenting with Promus PREMIER study stent.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Percutaneous coronary intervention (Promus PREMIER)

Interventional coronary artery stenting with Promus PREMIER study stent.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patient must be at least 18 years of age
* Patient must sign informed consent form
* Patient has received at least one Promus PREMIER stent
* Patient self-identifies as one or more of the following:

* Female
* Black of African Heritage
* Hispanic/Latino
* American Indian or Alaska native

Exclusion Criteria

* Not applicable
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Boston Scientific Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Roxana Mehran, MD

Role: PRINCIPAL_INVESTIGATOR

Icahn School of Medicine at Mount Sinai

Wayne Batchelor, MD

Role: PRINCIPAL_INVESTIGATOR

Tallahassee Memorial Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

St Luke's Medical Center

Phoenix, Arizona, United States

Site Status

St Bernards Heart and Vascular

Jonesboro, Arkansas, United States

Site Status

Arkansas Cardiology/Baptist Health Medical Center

Little Rock, Arkansas, United States

Site Status

Central Cardiology Medical Clinic

Bakersfield, California, United States

Site Status

Sharp Chula Vista Medical Center

Chula Vista, California, United States

Site Status

Cardiovascular Consultants Heart Center

Fresno, California, United States

Site Status

UCLA Medical Center

Los Angeles, California, United States

Site Status

Mercy General Hospital

Sacramento, California, United States

Site Status

Capital Research Institute

Washington D.C., District of Columbia, United States

Site Status

Bay Area Cardiology

Brandon, Florida, United States

Site Status

Research Physicians Network Alliance

Hollywood, Florida, United States

Site Status

Memorial Hospital Jacksonville

Jacksonville, Florida, United States

Site Status

Cardiovascular Institute of Northwest Florida

Panama City, Florida, United States

Site Status

Charlotte Heart & Vascular

Port Charlotte, Florida, United States

Site Status

Tallahassee Memorial Hospital

Tallahassee, Florida, United States

Site Status

Pepin Heart Hospital and Dr. Kiran C. Patel Research Institute

Tampa, Florida, United States

Site Status

Emory University

Atlanta, Georgia, United States

Site Status

University Hospital

Augusta, Georgia, United States

Site Status

Redmond Regional Medical Center

Rome, Georgia, United States

Site Status

University of Chicago Medical Center

Chicago, Illinois, United States

Site Status

Presence Saint Joseph Medical Center

Joliet, Illinois, United States

Site Status

The Heart Center of Lake County

Merrillville, Indiana, United States

Site Status

University of Iowa Hospitals and Clinics

Iowa City, Iowa, United States

Site Status

Cardiovascular Research, LLC (Willis-Knighton)

Shreveport, Louisiana, United States

Site Status

MedStar Union Memorial Hospital

Baltimore, Maryland, United States

Site Status

Suburban Hospital

Bethesda, Maryland, United States

Site Status

Delmarva Heart Research Foundation

Salisbury, Maryland, United States

Site Status

Baystate Medical Center

Springfield, Massachusetts, United States

Site Status

CCA Research

Gulfport, Mississippi, United States

Site Status

North Kansas City Hospital

North Kansas City, Missouri, United States

Site Status

St. Louis Heart and Vascular

St Louis, Missouri, United States

Site Status

Jersey Shore University Medical Center

Neptune City, New Jersey, United States

Site Status

Mount Sinai Hospital

New York, New York, United States

Site Status

Montefiore Medical Center

The Bronx, New York, United States

Site Status

Novant Health Heart and Vascular Institute

Charlotte, North Carolina, United States

Site Status

NC Heart and Vascular Research

Raleigh, North Carolina, United States

Site Status

INTEGRIS Baptist Medical Center

Oklahoma City, Oklahoma, United States

Site Status

Presbyterian University Hospital

Pittsburgh, Pennsylvania, United States

Site Status

Lankenau Medical Center

Wynnewood, Pennsylvania, United States

Site Status

Palmetto Health

Columbia, South Carolina, United States

Site Status

St. Francis Physician Services Inc., DBA Upstate Cardiology

Greenville, South Carolina, United States

Site Status

Seton Heart Institute

Austin, Texas, United States

Site Status

Methodist Hospital Dallas

Dallas, Texas, United States

Site Status

VA North Texas Health Care System

Dallas, Texas, United States

Site Status

Plaza Medical Center of Forth Worth

Fort Worth, Texas, United States

Site Status

University of Texas Medical Branch at Galveston

Galveston, Texas, United States

Site Status

St. Luke's Episcopal Hospital

Houston, Texas, United States

Site Status

Christus Santa Rosa Hospital-City Center

New Braunfels, Texas, United States

Site Status

The University of Vermont Medical Center

Burlington, Vermont, United States

Site Status

Virginia Mason

Seattle, Washington, United States

Site Status

Cardiac Study Center

Tacoma, Washington, United States

Site Status

CAMC Clinical Trials Center

Charleston, West Virginia, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

References

Explore related publications, articles, or registry entries linked to this study.

Batchelor W, Kandzari DE, Davis S, Tami L, Wang JC, Othman I, Gigliotti OS, Haghighat A, Singh S, Lopez M, Giugliano G, Horwitz PA, Chandrasekhar J, Underwood P, Thompson CA, Mehran R. Outcomes in Women and Minorities Compared With White Men 1 Year After Everolimus-Eluting Stent Implantation: Insights and Results From the PLATINUM Diversity and PROMUS Element Plus Post-Approval Study Pooled Analysis. JAMA Cardiol. 2017 Dec 1;2(12):1303-1313. doi: 10.1001/jamacardio.2017.3802.

Reference Type BACKGROUND
PMID: 29049508 (View on PubMed)

Epps K, Goel R, Mehran R, Kandzari D, Damluji A, Tehrani B, Sherwood M, Truesdell A, Davis S, Wang JC, Lopez M, Singh S, Underwood P, Allocco D, Batchelor W. Influence of Race/Ethnicity and Sex on Coronary Stent Outcomes in Diabetic Patients. J Soc Cardiovasc Angiogr Interv. 2023 Sep-Oct;2(5):101053. doi: 10.1016/j.jscai.2023.101053. Epub 2023 Aug 4.

Reference Type DERIVED
PMID: 38469035 (View on PubMed)

Beerkens FJ, Cao D, Batchelor W, Sartori S, Kandzari DE, Davis S, Tamis L, Wang JC, Othman I, Vogel B, Spirito A, Subramaniam V, Gigliotti OS, Haghighat A, Feng Y, Singh S, Lopez M, Giugliano G, Horwitz PA, Dangas G, Mehran R. Percutaneous Coronary Intervention in Men, Women, and Minorities With a Previous Coronary Artery Bypass Graft Surgery (from the Pooled PLATINUM Diversity and PROMUS Element Plus Registries). Am J Cardiol. 2023 Aug 1;200:204-211. doi: 10.1016/j.amjcard.2023.05.028. Epub 2023 Jun 22.

Reference Type DERIVED
PMID: 37354778 (View on PubMed)

Batchelor WB, Damluji AA, Yong C, Fiuzat M, Barnett SD, Kandzari DE, Sherwood MW, Epps KC, Tehrani BN, Allocco DJ, Meredith IT, Lindenfeld J, O'Connor CM, Mehran R. Does study subject diversity influence cardiology research site performance?: Insights from 2 U.S. National Coronary Stent Registries. Am Heart J. 2021 Jun;236:37-48. doi: 10.1016/j.ahj.2021.02.003. Epub 2021 Feb 24.

Reference Type DERIVED
PMID: 33636137 (View on PubMed)

Mehran R, Chandrasekhar J, Davis S, Nathan S, Hill R, Hearne S, Vismara V, Pyo R, Gharib E, Hawa Z, Chrysant G, Kandzari D, Underwood P, Allocco DJ, Batchelor W. Impact of Race and Ethnicity on the Clinical and Angiographic Characteristics, Social Determinants of Health, and 1-Year Outcomes After Everolimus-Eluting Coronary Stent Procedures in Women. Circ Cardiovasc Interv. 2019 Apr;12(4):e006918. doi: 10.1161/CIRCINTERVENTIONS.118.006918.

Reference Type DERIVED
PMID: 30998393 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

S2326

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

PE PREMIER CHINA CLINICAL TRIAL
NCT02230254 COMPLETED NA
Clinical Investigation for Everolimus Drug Eluting Stent
NCT06769217 ACTIVE_NOT_RECRUITING PHASE4