Study Results
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View full resultsBasic Information
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COMPLETED
NA
71 participants
INTERVENTIONAL
2013-01-31
2016-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
SINGLE
Study Groups
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Behavioural Intervention/Feedback
The behavioral interventionist will contact the patient and parent by email and telephone to schedule a telephone call to review the downloaded adherence information and discuss barriers experienced by the patient/parent using a standard script. The behavioral feedback will be administered three times: at 1-, 2- and 3-months post-baseline.
Motivational Interview
Video Attention Control
The patients in this arm of the study will be emailed a link to an educational video about Pediatric MS and therapy for MS at three time points: 1-, 2-, and 3-months post-baseline.
Video Attention Control
Interventions
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Motivational Interview
Video Attention Control
Eligibility Criteria
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Inclusion Criteria
* Have a diagnosis of MS, as per revised McDonald diagnostic criteria and International Pediatric MS Study Group criteria;
* Prescribed with an oral or injectable disease-modifying therapy for MS for at least six months.
Exclusion Criteria
* Patients on IV DMT will not be included in the study.
* Non-English speaking patients
10 Years
18 Years
ALL
No
Sponsors
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National Multiple Sclerosis Society
OTHER
Loma Linda University
OTHER
University of Pittsburgh
OTHER
Children's Hospital of Philadelphia
OTHER
Boston Children's Hospital
OTHER
Baylor College of Medicine
OTHER
University of Alabama at Birmingham
OTHER
Mayo Clinic
OTHER
University of Colorado, Denver
OTHER
University of California, San Francisco
OTHER
Washington University School of Medicine
OTHER
Alberta Children's Hospital
OTHER
The Cleveland Clinic
OTHER
DeltaQuest Foundation
UNKNOWN
The Hospital for Sick Children
OTHER
Responsible Party
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E. Ann Yeh
Staff Neurologist
Principal Investigators
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E. Ann Yeh, MD
Role: PRINCIPAL_INVESTIGATOR
University of Toronto, The Hospital for Sick Children
Locations
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University of Alabama
Birmingham, Alabama, United States
Loma Linda University
Loma Linda, California, United States
The Regents of the University of California, San Francisco
San Francisco, California, United States
University of Colorado at Denver
Denver, Colorado, United States
Boston Children's Hospital
Boston, Massachusetts, United States
Mayo Clinic
Rochester, Minnesota, United States
Washington University
St Louis, Missouri, United States
Cleveland Clinic
Cleveland, Ohio, United States
The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
University of Pittsburgh
Pittsburgh, Pennsylvania, United States
Baylor College of Medicine
Houston, Texas, United States
Alberta Children's Hospital
Calgary, Alberta, Canada
The Hospital for Sick Children
Toronto, Ontario, Canada
Countries
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References
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Yeh EA, Chiang N, Darshan B, Nejati N, Grover SA, Schwartz CE, Slater R, Finlayson M; Pediatric MS Adherence Study Group. Adherence in Youth With Multiple Sclerosis: A Qualitative Assessment of Habit Formation, Barriers, and Facilitators. Qual Health Res. 2019 Apr;29(5):645-657. doi: 10.1177/1049732318779039. Epub 2018 Jun 17.
Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE; Pediatric MS Adherence Study Group. Correction to: Impact of an electronic monitoring device and behavioural feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial. Qual Life Res. 2018 Apr;27(4):1117. doi: 10.1007/s11136-017-1773-4.
Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE; Pediatric MS Adherence Study Group. Impact of an electronic monitoring device and behavioral feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial. Qual Life Res. 2017 Sep;26(9):2333-2349. doi: 10.1007/s11136-017-1571-z. Epub 2017 Apr 9.
Schwartz CE, Grover SA, Powell VE, Noguera A, Mah JK, Mar S, Mednick L, Banwell BL, Alper G, Rensel M, Gorman M, Waldman A, Schreiner T, Waubant E, Yeh EA. Risk factors for non-adherence to disease-modifying therapy in pediatric multiple sclerosis. Mult Scler. 2018 Feb;24(2):175-185. doi: 10.1177/1352458517695469. Epub 2017 Feb 1.
Other Identifiers
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HC 0148
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
1000035924
Identifier Type: -
Identifier Source: org_study_id
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