InSpace™ System in Comparison to Best Repair of Massive Rotator Cuff Tear.

NCT ID: NCT02208440

Last Updated: 2020-06-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-07-31

Study Completion Date

2019-01-31

Brief Summary

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This is a post-marketing study to further assess the safety and effectiveness of the InSpace™ device implantation in comparison to surgical repair of full thickness Massive Rotator Cuff Tear .

Detailed Description

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This is a post-marketing study to further assess the safety and effectiveness of the InSpace™ device implantation in comparison to surgical repair of full thickness Massive Rotator Cuff Tear .

The effectiveness will be assessed by comparing the shoulder outcome scores of each treatment arm ( ASES, Constant and Quick DASH) from pre-operation (baseline) up to 2 years post-operation, with respect to pain reduction, improvement of activity of daily living (ADL) and improvement of range of motion (ROM).

The safety will be asses by comparing the Adverse event rate between the treatment arms.

Conditions

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Full-thickness Rotator Cuff Tear

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
The patient is blinded to the treatment type

Study Groups

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Best Repair of torn Rotator Cuff

Subjects will undergo surgical intervention (usually arthroscopy) to perform debridement, acromioplasty if deemed necessary, long head of biceps tenotomy, and at least partial repair.

Group Type SHAM_COMPARATOR

Best Repair of torn Rotator Cuff

Intervention Type PROCEDURE

InSpace™ system

Subjects will undergo surgical intervention (usually arthroscopy or mini invasive) of debridement, acromioplasty if deemed necessary with or without long head of biceps tenotomy, and placement of the InSpace™ system.

Group Type ACTIVE_COMPARATOR

InSpace™ system

Intervention Type DEVICE

Interventions

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Best Repair of torn Rotator Cuff

Intervention Type PROCEDURE

InSpace™ system

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age 40 or older.
* Positive diagnostic imaging of the affected shoulder indicating full thickness Massive RCT involving more than one tendon.
* Persistent pain and functional disability of the affected shoulder for at least 3 months.

Exclusion Criteria

* Known allergy to the balloon material (copolymer of PLA and -θ-caprolactone).
* Evidence of significant osteoarthritis or cartilage damage in the shoulder
* Evidence of gleno-humeral instability
* Previous surgery of the shoulder in the past 2 years, excluding diagnostic arthroscopy
* Evidence of major joint trauma, infection, or necrosis in the shoulder
* Partial-thickness tears of the rotator cuff
Minimum Eligible Age

40 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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OrthoSpace Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Wigan and Leigh NHS Foundation Trust: Upper Limb & Trauma Surgery

Wigan, Hall Lane, Appley Bridge, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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IS-CL-02-UK

Identifier Type: -

Identifier Source: org_study_id

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