Dosage Calculation for Vitamin D Treatment

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

31 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-01-31

Study Completion Date

2013-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Severe vitamin D deficiency can be treated with oral loading doses of cholecalciferol. Our objective was to determine how to calculate the quantity of cholecalciferol needed for supplementation by single algorithm, usable on a patient-to-patient basis.

We've conducted two studies. Study 1 was done retroactively and included 88 patients treated for low vitamin D, 60 of those with a loading dose. The second study included 29 patients and aimed to test the validity of an algorithm based on data from study 1, which included patient BMI. Both studies used oral loading doses and daily supplementation of cholecalciferol.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

A Prospective Open-label Comparison of Two Vitamin D3 Repletion Strategies in Vitamin D Deficient Patients

NCT01650883

Vitamin D 25 OH Deficiency

COMPLETED NA

Change in Free 25(OH)D After High Dose in Vitamin D Deficient Postmenopausal Women

NCT02553044

Vitamin D Deficiency Osteoporosis

COMPLETED NA

Effect of Vitamin D Oral Supplements on 25 OH Vitamin D Levels

NCT01170494

Vitamin D Deficiency

COMPLETED NA

Cholecalciferol and Calcifediol Are Both Useful to Improve Vitamin D Serum Levels

NCT06138249

Hypovitaminosis D

RECRUITING NA

A Study on Oral Vitamin D Megadoses

NCT01067898

Hypovitaminosis D

COMPLETED PHASE4

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Deficiency, Vitamin D Obesity

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Loading dose substitution

Substituted with a highdose of cholecalciferol at study start

Group Type EXPERIMENTAL

Cholecalciferol

Intervention Type DRUG

Historic controls

Control subjects from journal archive

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Cholecalciferol

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Dekristol capsules of 20.000 IU pr. capsule

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* severe hypovitaminosis D (25OH-vit.D \<25 nmol/L)

Exclusion Criteria

* Malabsorption
* Renal disease
* Other treatment with vitamin D related products
* Patients with a recent travel history with suspected increased sun exposure

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No