The Study of Genes Localization for Female Pelvic Floor Dysfunction

NCT ID: NCT02166528

Last Updated: 2014-06-18

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 200 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2013-11-30
• Study Completion Date: 2017-10-31

Brief Summary

Female pelvic floor dysfunction (FPD) is due to defects in the pelvic support structures, degradation, damage or dysfunction. The main problem of which is pelvic organ prolapse(POP), urinary incontinence(UI) and genital tract injury. Although it does not pose a serious threat to life, but affect the patient's quality of life seriously in the physical, psychological, social behavior and other aspects. With the growing aging population, the incidence rate has gradually increased, and increasing demands for people's quality of life simultaneously, more and more attention was raised to PFD as common chronic diseases.

In recent years, the basic research, epidemiology, prevention, diagnosis and treatment of PFD have made great progress, especially in developing gynecological urology theory and reconstructive pelvic surgery. But overall the basic research of PFD is lagging behind, especially susceptibility gene localization and functional studies did not get enough attention.

Conditions

Female Pelvic Floor Dysfunction

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: PROSPECTIVE

Study Groups

experiment group

patients with FPFD

No interventions assigned to this group

control group

patients without FPFD

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

1. female aging from 30 to 70-year old;

2. preoperative diagnosis of gynecologic malignancies;

3. have the ability to comply with Research programs;

4. voluntarily participate in the study and signed an informed consent form

Exclusion Criteria

1. patients with severe cardiovascular diseases, kidney, liver and other vital organs diseases, bone marrow disease and mental illness;

2. patients suffering from autoimmune diseases;

3. patients with acute infectious disease or infection early phase of infection;

4. patients with urinary tract infection;

5. patients with infection or erosion of ano-genital skin;

6. for any other reason, the researchers considered unsuitable for inclusion.

• Minimum Eligible Age: 30 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Shenzhen Huada Genomics Co., Ltd.

UNKNOWN

Sponsor Role: collaborator

Zhiqing, Liang

OTHER

Sponsor Role: lead

Responsible Party

Zhiqing, Liang

Director of Obstetrics and Gynecology

Responsibility Role: SPONSOR_INVESTIGATOR

Locations

Department of Obstetrics and Gynaecology, Southwest Hospital, Third Military

Chongqing, Chongqing Municipality, China

Countries

China

Other Identifiers

002

Identifier Type: -

Identifier Source: org_study_id