Evaluate St Jude Medical Prodigy Neuromodulation for FBSS or Chronic Pain of the Trunk and/or Limbs

NCT ID: NCT02143791

Last Updated: 2024-07-08

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

126 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-06-30

Study Completion Date

2016-10-31

Brief Summary

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The purpose of this study is to confirm long term efficacy and safety of the ProdigyTM neuromodulation system in the management of failed back surgery syndrome or chronic intractable pain of the trunk and/or limbs.

Detailed Description

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Conditions

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Chronic Pain

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Burst and Tonic stimulation

All subjects were required to receive BurstDR stimulation therapy for the first 3 months after permanent implant. Thereafter the stimulation mode could be changed to tonic stimulation depending on patient's preference or physician's discretion.

Group Type EXPERIMENTAL

Burst and Tonic stimulation

Intervention Type PROCEDURE

Interventions

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Burst and Tonic stimulation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patient with chronic, intractable pain of the trunk and/or limbs, including unilateral or bilateral pain associated with the following: failed back surgery syndrome or intractable low back and/or leg pain
* Patient diagnosed with radiculopathy
* Patient diagnosed with neuropathic pain
* Patient is considered by the investigator as a candidate for implantation of a SCS system
* Patient is ≥ 18 years of age
* Patient must be willing and able to comply with study requirements
* Patient must indicate his/her understanding of the study and willingness to participate by signing an appropriate Informed Consent Form

Exclusion Criteria

* Patient is diagnosed with ischemic pain
* Patient is diagnosed with arachnoiditis
* Patient is diagnosed with complex regional pain syndrome (CRPS I and II)
* Patient is diagnosed with peripheral vascular disease (PVD)
* Patient is diagnosed with diabetic neuropathic pain
* Patient is diagnosed with chronic migraine
* Patient is immune-compromised
* Patient has history of cancer requiring active treatment in the last 6 months
* Patient has a documented history of substance abuse (narcotics, alcohol, etc.) or substance dependency in the last 6 months
* Patients with a SCS system or implantable infusion pump implanted previously
* Patient has a life expectancy of less than one year
* Patient is pregnant or is planning to become pregnant during the duration of the investigation
* Patient is unable to comply with the follow up schedule
* Patient needing legally authorized representative
* Patient unable to read and write
* Patient is currently participating in another clinical investigation with an active treatment arm.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abbott Medical Devices

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tony Van Havenbergh

Role: PRINCIPAL_INVESTIGATOR

St Augustinus, Wilrijk, Belgium

Devyani Nanduri

Role: STUDY_DIRECTOR

Abbott Medical Devices

Locations

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Metro Spinal Clinic

Caulfield, , Australia

Site Status

Frankston Pain Management

Frankston, , Australia

Site Status

Epworth Hospital

Richmond, , Australia

Site Status

St Augustinus Ziekenhuis

Wilrijk, Antwerp, Belgium

Site Status

Medizinische Einrichtungen der Universität zu Köln

Cologne, , Germany

Site Status

University Hospital

Düsseldorf, , Germany

Site Status

Hospital Gera

Gera, , Germany

Site Status

Universitätsklinik für Stereataktische Neurochirurgie

Magdeburg, , Germany

Site Status

Universitatsklinikum Tubingen

Tübingen, , Germany

Site Status

St Vincents University Hospital

Dublin, , Ireland

Site Status

Azienda Ospedaliera Monaldi

Napoli, , Italy

Site Status

Az. Ospedaliero-Universitaria Pisana - Stabilimento Santa Chiara

Pisa, , Italy

Site Status

Az. Osp.S.Giovanni Addolorata

Roma, , Italy

Site Status

Medisch Spectrum Twente

Enschede, , Netherlands

Site Status

St Antonius Ziekenhuis

Nieuwegein, , Netherlands

Site Status

Stichting Alysis Zorggroep

Velp, , Netherlands

Site Status

Hospital Virgen de Rocio

Seville, , Spain

Site Status

University Hospital

Uppsala, , Sweden

Site Status

Seacroft Hospital

Leeds, , United Kingdom

Site Status

St Bartolomew's

London, , United Kingdom

Site Status

James Cook University Hospital

Middlesbrough, , United Kingdom

Site Status

Countries

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Australia Belgium Germany Ireland Italy Netherlands Spain Sweden United Kingdom

Other Identifiers

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NM-13-038-ID-SC

Identifier Type: -

Identifier Source: org_study_id

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