Epidemiology of Sudden Cardiac Arrest in Sub-Saharan Africa: Rationale and Design

NCT ID: NCT02142270

Last Updated: 2014-05-20

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 250000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2015-01-31
• Study Completion Date: 2018-01-31

Brief Summary

Background The burden of sudden cardiac death (SCD) in Africa is unknown. Our aim is to assess the epidemiology of SCD in Africa. Methods The sub-Saharan Africa SCD study is a prospective, multicenter, community-based registry monitoring all cases of cardiac arrest occurring in victims > 15 years old. Investigators will use the definition of established SCD if an unexpected death without obvious extracardiac cause, occurred with a rapid witnessed collapse, or if unwitnessed, occurred within 1 hour after the onset of symptoms; probable SCD if an unexpected death without obvious extracardiac cause occurred within the previous 24 hours. After approval from institutional boards, Investigators will record demographic, clinical, electrocardiographic and biological variables of SCD victims (including survivors of cardiac arrest) in several sub-Saharan African cities. All deaths occurring in residents of districts of interest will be checked for past medical history, circumstances of death, and autopsy report (if possible). Investigators will also analyze the employment of resuscitation attempts during the timeframe of sudden cardiac arrest (SCA) in various patient populations throughout countries. Conclusion This study will provide comprehensive, contemporary data on the epidemiology of SCD in sub-Saharan Africa and will help in the development of strategies to prevent and manage cardiac arrest in this region of the world.

Conditions

Cardiovascular Diseases

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Victims of cardiac arrest, either SCD or aborted SCA

No interventions assigned to this group

Premature death

All residents of districts of interest will be surveyed during 3 years. premature deaths occurring in residents of districts of interest will be checked for past medical history, circumstances of death, and autopsy report (if possible). Investigators will also analyze the employment of resuscitation attempts during the timeframe of sudden cardiac arrest (SCA) in various patient populations throughout African countries.

The arm group of the study is every resident of the district of interest

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Victims of cardiac arrest, either SCD or aborted SCA

Exclusion Criteria

• Age ≤ 15 years.
• Refusal of consent (by the family).

• Minimum Eligible Age: 15 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Cameroon Resuscitation Council

OTHER

Sponsor Role: lead

Responsible Party

BONNY Aimé

Principal investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Bonny

Douala, , Cameroon

Countries

Cameroon

Central Contacts

Aime Bonny

Role: CONTACT

aimebonny@yahoo.fr

33637975227

Facility Contacts

Aime Bonny

Role: primary

aimebonny@yahoo.fr

33637975227

Other Identifiers

PASCAR

Identifier Type: -

Identifier Source: org_study_id