Thrombin Generation and Gestational Outcome

NCT ID: NCT02139670

Last Updated: 2018-03-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

29 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-10-31

Study Completion Date

2017-12-31

Brief Summary

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In total 120 pregnant women's with history of recurrent miscarriages, are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant. The investigators will measure the thrombin generation in plasma assessed by the calibrated automated thrombogram (CAT). The relation between pregnancy outcome and thrombin measurements will be determined

Detailed Description

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Conditions

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Thrombophilia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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pregnant womens

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* age \> 18
* signed inform consent
* first trimester
* two early miscarriages(before week 10) or one later abortions (after week 10)

Exclusion Criteria

* Chronic treatment with aspirin or other anticoagulants
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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HaEmek Medical Center, Israel

OTHER

Sponsor Role lead

Responsible Party

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Elias mazen

Director of Internal medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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mazen elias, prof

Role: PRINCIPAL_INVESTIGATOR

HaEmek Medical Center, Israel

Locations

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Haemek medical center

Afula, , Israel

Site Status

Countries

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Israel

Other Identifiers

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thrombin generation- pregnancy

Identifier Type: -

Identifier Source: org_study_id

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