The Effect of Glucagon-Like Peptide-1 (GLP-1) on Pulmonary Vascular Resistance (PVR) in Patients With Heart Failure
NCT ID: NCT02129179
Last Updated: 2018-04-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
10 participants
INTERVENTIONAL
2014-06-30
2016-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
BASIC_SCIENCE
NONE
Study Groups
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GLP-1
Glucagon-Like Peptide 1
Interventions
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Glucagon-Like Peptide 1
Eligibility Criteria
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Inclusion Criteria
* Able to give informed consent
* On the waiting list for heart transplant
* Left Ventricular Dysfunction awaiting catheterisation
Exclusion Criteria
* Women of child bearing age and breast feeding women
* Cardiac pacemaker or other implanted metallic device
* Unable to give informed consent
18 Years
ALL
No
Sponsors
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Papworth Hospital NHS Foundation Trust
OTHER_GOV
Responsible Party
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Locations
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Papworth Hospital NHS Foundation Trust
Papworth Everard, , United Kingdom
Countries
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References
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Clarke SJ, Pettit S, Giblett JP, Zhao T, Kydd AC, Albrechtsen NJW, Deacon CF, Parameshwar J, Hoole SP. Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure: A Pilot Study. Clin Ther. 2019 Jan;41(1):118-127.e0. doi: 10.1016/j.clinthera.2018.11.013. Epub 2018 Dec 28.
Other Identifiers
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PO1860
Identifier Type: -
Identifier Source: org_study_id
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