Etiological Factors, Risk Factors and Early Stages of Chronic Disease in Different Degrees of Childhood Overweight

NCT ID: NCT02091544

Last Updated: 2020-04-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-04-30

Study Completion Date

2023-04-30

Brief Summary

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Children and adolescents with overweight and obesity are predisposed to significant health problems. It is known that childhood obesity can adversely affect almost every organ system, and if left untreated, the major impact of childhood overweight is likely to be felt in the next generation of adults.

The aim of " Kijk op overgewicht bij kinderen" is to collect and follow-up longitudinal data from a population of different degrees of children with overweight regarding etiological factors, risk factors and early stages of chronic disease in different degrees of childhood overweight.

Detailed Description

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Furthermore, from april 2020 onwards, a prospective sub study will be conducted. This sub study aims to investigate the changes in lifestyle behaviour of children with overweight or obesity and their families during the COVID-19 pandemic, including the (governmental) measures taken for this, and the effect of obesity and different weight-related risk factors on the host response of these children.

The goal of this sub study is to collect data to enable analyses for future research questions regarding the influence of the COVID-19 on the lifestyle of a child with overweight and their family. Endpoints are for example physical activity, eating behavior, BMI-z score, remote lifestyle coaching, quality of life and parental practices regarding nutrition and physical activity behavior. We will also measure symptoms associated with COVID-19 and the host response that target COVID-19.

Conditions

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Childhood Obesity

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Lifestyle intervention

lifestyle intervention

Lifestyle intervention

Intervention Type OTHER

Interventions

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Lifestyle intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Participation in the COACH program
* Aged till 18 years old (at time of inclusion)
* Overweight or obesity according to International Obesity Task Force (IOTF) criteria

Exclusion Criteria

• None
Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Maastricht University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anita Vreugdenhil, Dr

Role: PRINCIPAL_INVESTIGATOR

Maastricht University Medical Center

Luc Zimmermann, Prof.dr.

Role: STUDY_CHAIR

Maastricht University Medical Center

Locations

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Maastricht University Medical Center

Maastricht, Limburg, Netherlands

Site Status RECRUITING

Countries

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Netherlands

Central Contacts

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Anita Vreugdenhil, Dr

Role: CONTACT

0031 (0)43 387 5284

Kylie Karnebeek, Drs

Role: CONTACT

0031 (0)43 387 4402

Facility Contacts

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Anita Vreugdenhil, Dr.

Role: primary

0031 (0)43 387 5284

Kylie Karnebeek, Drs.

Role: backup

0031 (0)43 387 4402

References

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van Dam MJCM, Pottel H, Delanaye P, Vreugdenhil ACE. The evaluation of kidney function estimation during lifestyle intervention in children with overweight and obesity. Pediatr Nephrol. 2024 Nov;39(11):3271-3278. doi: 10.1007/s00467-024-06435-0. Epub 2024 Jul 4.

Reference Type DERIVED
PMID: 38963556 (View on PubMed)

Lubrecht J, Arayess L, Reijnders D, Hesselink ML, Velde GT, Janse A, von Rosenstiel I, van Mil EGAH, Verweij M, Vreugdenhil ACE. Weight Gain in Children during the COVID-19 Pandemic and the Protective Effect of Lifestyle Intervention in Children with Obesity. Obes Facts. 2022;15(4):600-608. doi: 10.1159/000525298. Epub 2022 May 31.

Reference Type DERIVED
PMID: 35640561 (View on PubMed)

van Dam MJCM, Pottel H, Vreugdenhil ACE. Creatinine-based GFR-estimating equations in children with overweight and obesity. Pediatr Nephrol. 2022 Oct;37(10):2393-2403. doi: 10.1007/s00467-021-05396-y. Epub 2022 Feb 24.

Reference Type DERIVED
PMID: 35211793 (View on PubMed)

Ten Velde G, Plasqui G, Dorenbos E, Winkens B, Vreugdenhil A. Objectively measured physical activity and sedentary time in children with overweight, obesity and morbid obesity: a cross-sectional analysis. BMC Public Health. 2021 Aug 17;21(1):1558. doi: 10.1186/s12889-021-11555-5.

Reference Type DERIVED
PMID: 34404361 (View on PubMed)

Rijks JM, Plat J, Dorenbos E, Penders B, Gerver WM, Vreugdenhil ACE. Association of TSH With Cardiovascular Disease Risk in Overweight and Obese Children During Lifestyle Intervention. J Clin Endocrinol Metab. 2017 Jun 1;102(6):2051-2058. doi: 10.1210/jc.2016-3057.

Reference Type DERIVED
PMID: 28379580 (View on PubMed)

Rijks J, Karnebeek K, van Dijk JW, Dorenbos E, Gerver WJ, Stouthart P, Plat J, Vreugdenhil A. Glycaemic Profiles of Children With Overweight and Obesity in Free-living Conditions in Association With Cardiometabolic Risk. Sci Rep. 2016 Aug 18;6:31892. doi: 10.1038/srep31892.

Reference Type DERIVED
PMID: 27534260 (View on PubMed)

Rijks J, Penders B, Dorenbos E, Straetemans S, Gerver WJ, Vreugdenhil A. Pituitary response to thyrotropin releasing hormone in children with overweight and obesity. Sci Rep. 2016 Aug 3;6:31032. doi: 10.1038/srep31032.

Reference Type DERIVED
PMID: 27485208 (View on PubMed)

Related Links

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Other Identifiers

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COACH

Identifier Type: -

Identifier Source: org_study_id

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