Effectiveness and Safety Study of the Dexcom G4 Platinum With Modified Algorithm

NCT ID: NCT02087995

Last Updated: 2017-08-24

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-12-31

Study Completion Date

2014-03-31

Brief Summary

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To establish the performance of the Dexcom G4 Platinum with a Modified Algorithm continuous monitoring system when compared to a laboratory reference measurement.

Detailed Description

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A study to evaluate the performance of a modification to the G4 Platinum CGM system in adults with diabetes.

Conditions

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Diabetes Mellitus

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Continuous Glucose Monitoring System

Single-Arm, CGM Device Glucose challenge performed during a clinic session to obtain accuracy data for the CGM system compared to a venous reference measurement

Group Type EXPERIMENTAL

Continuous Glucose Monitoring

Intervention Type DEVICE

A prescribed clinic session day for participating subjects.

Interventions

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Continuous Glucose Monitoring

A prescribed clinic session day for participating subjects.

Intervention Type DEVICE

Other Intervention Names

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CGM System G4 Platinum CGM System Dexcom G4 CGM System

Eligibility Criteria

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Inclusion Criteria

* Ages 18 years or older
* Diagnosis of Type 1 diabetes or Type 2 diabetes on Intensive Insulin Therapy (ITT)
* Willing to participate in a clinic session

Exclusion Criteria

* Use of Acetaminophen during study period
* Pregnancy
* Hematocrit (HCT) \<35% (females) and 38% (males)
* Dialysis, history of cardiovascular disease, epilepsy, severe migraines in the past 6 months, adrenal disease, syncope, significant hypoglycemia unawareness, or a history of severe hypoglycemia within the last 6 months.
* Any condition that, in the opinion of the Investigator, would interfere with their participation in the study or pose and excessive risk to study staff.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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DexCom, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Andy Balo

Role: STUDY_CHAIR

DexCom, Inc.

Locations

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John Muir Physician Network Clinical Research

Concord, California, United States

Site Status

AMCR Institute

Escondido, California, United States

Site Status

Diablo Clinical Research, Inc.

Walnut Creek, California, United States

Site Status

Countries

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United States

References

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Peyser TA, Nakamura K, Price D, Bohnett LC, Hirsch IB, Balo A. Hypoglycemic Accuracy and Improved Low Glucose Alerts of the Latest Dexcom G4 Platinum Continuous Glucose Monitoring System. Diabetes Technol Ther. 2015 Aug;17(8):548-54. doi: 10.1089/dia.2014.0415. Epub 2015 May 11.

Reference Type DERIVED
PMID: 25961446 (View on PubMed)

Other Identifiers

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PTL901100

Identifier Type: -

Identifier Source: org_study_id

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