Natural History and Biological Study of Netherton Syndrome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

18 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-10-01

Study Completion Date

2016-09-04

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study aims at studying the natural history of Netherton syndrome (NS), to identify the consequences of LEKTI deficiency on the immune system and to characterize new molecular mechanisms involved in the disease.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Etiology Study of Kawasaki Disease

NCT00154596

Kawasaki Disease

UNKNOWN

The Prevalence and Impacts of Nudix Hydrolase 15 (NUDT15) Gene Variants in Taiwanese Inflammatory Bowel Disease

NCT06913998

Inflammatory Bowel Diseases Neutropenia Nudt15 Deficiency

RECRUITING

The Changes of Cytokines in Guillain Barré Syndrome: the Correlation With Clinical Manifestations and Skin Innervation

NCT00173199

Guillain Barré Syndrome

UNKNOWN

Evaluating Light-tissue Reaction and Transdermal Drug Delivery by Multiphoton Microscopy

NCT01355328

Healthy

UNKNOWN NA

The Study of Human Atherosclerosis by Polarization-Sensitive Optical Coherence Tomography

NCT00173238

Pathological Conditions, Anatomical

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Netherton Syndrome Healthy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Netherton syndrome

Patients with Netherton syndrome

Group Type ACTIVE_COMPARATOR

Biopsy

Intervention Type OTHER

Blood sample

Intervention Type OTHER

Healthy controls

healthy controls

Group Type ACTIVE_COMPARATOR

Biopsy

Intervention Type OTHER

Blood sample

Intervention Type OTHER

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Biopsy

Intervention Type OTHER

Blood sample

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Adult or child (no age limit)
* Confirmed diagnosis of Netherton syndrome
* Signed informed consent form for the patient or his legal representative