Adequate Definition of Delayed Graft Function in Living and Deceased Donor Kidney Transplantation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2016-12-31

Brief Summary

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It is required to establish an adequate definition of delayed graft function in deceased donor kidney transplantation. We attempt to compare various definitions of delayed graft function and find the definition that can predict graft function survival best in deceased donor kidney transplantation.

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Detailed Description

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Delayed graft function after kidney transplantation has been reported to be an important predictor for poor short and long-term survival. Delayed graft function increases post-transplantation morbidity, hospital stay, and incidence of premature graft failure. However, the definition of delayed graft function varies and more than ten definitions have been used in previous studies. Although the definition using dialysis requirements during seven days after transplantation has been used most frequently, dialysis may be required without any evidence of renal damage during one week after transplantation. Furthermore, the incidence of delayed graft function in living donor kidney transplantation using this definition has been reported to be relatively low (as low as 1.6%) compared with the incidence in deceased donor kidney transplantation (up to 50%). Therefore, it is required to establish a better definition of delayed graft function in deceased donor kidney transplantation. We attempt to compare various definitions of delayed graft function in deceased donor kidney transplantation and find the definition that can predict graft function survival best in deceased donor kidney transplantation.

Conditions

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Deceased Donor Kidney Transplantation Living Donor Kidney Transplantation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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patients who underwent kidney transplantation

patients who underwent living or deceased donor kidney transplantation between 2008 and 2013

kidney transplantation, living or deceased donor

Intervention Type PROCEDURE

Interventions

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kidney transplantation, living or deceased donor

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients who underwent living or deceased donor kidney transplantation between 2008 and 2013

Exclusion Criteria

* incomplete data of postoperative creatinine during ten days after transplantation or postoperative urine output during three days after transplantation
* patients who underwent retransplantation
* patients who expired for reasons other than kidney transplantation

Eligible Sex

ALL

Accepts Healthy Volunteers

No