Study of Vitamin A and Carbomer in Comforting the Ocular Surface Irritations of Glaucoma Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-09-30

Study Completion Date

2013-09-30

Brief Summary

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Most of the patients under long application of anti-glaucoma eyedrops endure severe ocular surface irritation, which interrupt their quality of life a lot. Lots of studies aimed to search for new drugs for therapy. The investigators hypothesized that the artificial tears containing vitamin A or carbomer may be a great substitute. Both of the two drugs were in common use and had already been tested in animals.

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Detailed Description

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Conditions

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Primary Open-angle Glaucoma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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vitamin A palmitate eye gel

0.1% vitamin A palmitate; Sinqi, Shenyang, China

Group Type EXPERIMENTAL

Vitamin A

Intervention Type DRUG

use one drop in the eye

carbomer eye gel

0.2% Carbomer 940; Bausch \& Lomb, Aschheim, Germany

Group Type EXPERIMENTAL

carbomer eye gel

Intervention Type DRUG

use one drop in the eye

Interventions

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Vitamin A

use one drop in the eye

Intervention Type DRUG

carbomer eye gel

use one drop in the eye

Intervention Type DRUG

Other Intervention Names

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vitamin A palmitate eye gel Carbomer Eye Drops

Eligibility Criteria

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Inclusion Criteria

\- diagnosed primary open-angle glaucoma or normal tension glaucoma patients with prostaglandin analogs treatment for more than one year.

Exclusion Criteria

1. any systemic diseases which may cause ocular damage;
2. previous ocular trauma or surgery;
3. contact lens wear history in previous 6 months;
4. application of any artificial tears 3 months ago;
5. allergic to any of the drugs we used during examination.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No