A Study to Describe Patterns of Care and Outcomes of Men Who Are at High Risk After Experiencing Biochemical Failure Following Definitive Prostate Cancer Therapy, Men With Castration-resistant Prostate Cancer and Men With Metastatic Prostate Cancer

NCT ID: NCT02066961

Last Updated: 2019-12-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1533 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-12-31

Study Completion Date

2019-11-14

Brief Summary

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The purpose of this study is to describe patterns in disease management and to describe clinical outcomes, as well as to identify factors influencing physician treatment decisions including reason(s) for treatment choices and trigger(s) for treatment changes and to document healthcare resource utilization used to manage treatment-related complications.

Detailed Description

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Each subject will be followed from the time of enrollment for a minimum of 3 years and a maximum of up to 6 years or until death, whichever comes first.

Conditions

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Prostate Cancer Castration-resistant Prostate Cancer Metastatic Prostate Cancer

Keywords

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metastatic prostate cancer castration-resistant prostate cancer prostate cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cohort 1

Subjects with biochemical failure experience after primary treatment and have high-risk disease

No interventions assigned to this group

Cohort 2

Subjects with a medical diagnosis of castration-resistant prostate cancer

No interventions assigned to this group

Cohort 3

Subjects with an initial diagnosis of metastatic prostate cancer

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of prostate adenocarcinoma
* Will receive a new intervention at the time of study entry, for the treatment of:

* Biochemical failure after initial curative-intent surgery (radical prostatectomy) or radiotherapy (external-beam radiation therapy, brachytherapy, or both) and a PSA doubling time of one year or less or a confirmed PSA of ≥ 50 ng/mL (2 consecutive values) within 6 months prior to study entry; or
* Castration-resistant prostate cancer; or
* Metastatic prostate cancer at initial diagnosis of prostate cancer

Exclusion Criteria

* Prior treatment of metastatic castration-resistant prostate cancer with systemic chemotherapy
* Life expectancy of \<1 year due to comorbidities
Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Astellas Pharma Global Development, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Senior Medical Director

Role: STUDY_DIRECTOR

Astellas Pharma Global Development, Inc.

Locations

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Algiers, , Algeria

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Algiers, , Algeria

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Blida, , Algeria

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Buenos Aires, , Argentina

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La Pampa, , Argentina

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Paraje Cabal, , Argentina

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Port Macquarie, New South Wales, Australia

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Tweed Heads, New South Wales, Australia

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Kurralta Park, South Australia, Australia

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Parkville, Victoria, Australia

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Richmond, Victoria, Australia

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Vienna, , Austria

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Belo Horizonte, Minas Gerais, Brazil

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Ijuí, Rio Grande do Sul, Brazil

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Passo Fundo, Rio Grande do Sul, Brazil

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Porto Alegre, Rio Grande do Sul, Brazil

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São Paulo, São Paulo, Brazil

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Caxias do Sul, , Brazil

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Santo André, , Brazil

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Granby, Quebec, Canada

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Québec, Quebec, Canada

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Bogotá, DC, Colombia

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Bogotá, DC, Colombia

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Cali, , Colombia

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Cairo, , Egypt

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Cairo, , Egypt

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Cairo, , Egypt

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Besançon, , France

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Lille, , France

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Nîmes, , France

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Pierre-Bénite, , France

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Poitiers, , France

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Saint-Mandé, , France

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Suresnes, , France

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Berlin, , Germany

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Freiburg im Breisgau, , Germany

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Hamburg, , Germany

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Jena, , Germany

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Nürtingen, , Germany

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Rostock, , Germany

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Ulm, , Germany

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Jakarta, , Indonesia

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Beer Ya'akov, Zerifin, Israel

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Haifa, , Israel

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Brescia, , Italy

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Cremona, , Italy

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Milan, , Italy

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Orbassano, , Italy

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Beirut, BA, Lebanon

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Beirut, BA, Lebanon

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Durango, , Mexico

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Amsterdam, , Netherlands

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Nijmegen, , Netherlands

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Hamilton, Waikato Region, New Zealand

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Christchurch, , New Zealand

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Tauranga, , New Zealand

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Tauranga, , New Zealand

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Muscat, , Oman

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Miraflores, Lima region, Peru

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Lima, , Peru

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Lima, , Peru

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Makati, , Philippines

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Pasig, , Philippines

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San Juan City, , Philippines

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Riyadh, , Saudi Arabia

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Singapore, , Singapore

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Singapore, , Singapore

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Singapore, , Singapore

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Singapore, , Singapore

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Anyang, , South Korea

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Busan, , South Korea

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Busan, , South Korea

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Incheon, , South Korea

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Seoul, , South Korea

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Seoul, , South Korea

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Seoul, , South Korea

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Suwon, , South Korea

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Vall d'Hebron 119-129, Barcelona, Spain

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Madrid, , Spain

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Sabadell, , Spain

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Guishan Township, Taoyuan County, Taiwan

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Kaohsiung City, , Taiwan

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Kaohsiung City, , Taiwan

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Taichung, , Taiwan

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Taipei, , Taiwan

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Taipei, , Taiwan

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Bangkok, , Thailand

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Phayathai, , Thailand

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Songkhla, , Thailand

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Hull, , United Kingdom

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London, , United Kingdom

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Newcastle upon Tyne, , United Kingdom

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Sunderland, , United Kingdom

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Countries

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Algeria Argentina Australia Austria Brazil Canada Colombia Egypt France Germany Indonesia Israel Italy Lebanon Mexico Netherlands New Zealand Oman Peru Philippines Saudi Arabia Singapore South Korea Spain Taiwan Thailand United Kingdom

Other Identifiers

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ONC-MA-1001

Identifier Type: -

Identifier Source: org_study_id