Essure (Model ESS310) Placement Rate Study

NCT ID: NCT02064413

Last Updated: 2021-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

134 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-03-17

Study Completion Date

2014-11-26

Brief Summary

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To evaluate the safety and successful placement rate of Essure Model ESS310 device and any factors that may influence the successful placement rate of this device.

Detailed Description

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Conditions

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Contraception

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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ESS310

All subjects that sign the informed consent and meet the eligibility criteria will be scheduled for an implant procedure.

Group Type EXPERIMENTAL

ESS310 (BAY1454032)

Intervention Type DEVICE

Interventions

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ESS310 (BAY1454032)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Females aged range 21 to 44 years
* Subjects seeking permanent contraception
* Subjects with body weight within range of 90-300 pounds (40 - 136 kilograms)
* Subjects for whom medical history indicates bilateral viable and patent fallopian tubes
* Subjects are able and willing to comply with the protocol required follow-up visits
* Subjects have fulfilled local requirements for counseling and consent to contraception and sterilization, including any required waiting periods
* Subjects provide written informed consent prior to enrolment
* Subjects who have sufficient mental capacity to understand the informed consent form (ICF), comply with the protocol requirements, and provide clinically relevant and reliable feedback regarding their experience implant and subsequent wearing of the device
* Subjects who agree that anonymized personal data will be made available to study Sponsor and requisite regional and international regulatory bodies

Exclusion Criteria

* Subjects suspected of being or confirmed pregnant
* Subjects post-partum or undergone pregnancy termination ≤6 weeks of scheduled insert placement
* Subjects who have known proximal tubal occlusion in either fallopian tube
* Subjects who have undergone fallopian tube sterilization procedure
* Subjects who have had total or partial salpingectomies
* Subjects diagnosed with tubal, endometrial, or myometrial pathology which may prevent fallopian tube ostia access
* Subjects diagnosed with unicornuate uterus
* Subjects diagnosed with active or currently being treated upper or lower pelvic infection
* Subjects with gynecologic malignancy
* Subjects who are currently taking corticosteroids
* Subjects with a known allergy to all contrast media available for use in HSG (Hysterosalpingogram)
* Subjects scheduled to undergo concomitant intrauterine procedures at the time of insert placement (e.g., endometrial ablation, fibroid resection by hysteroscopy, endometrial polypectomy). Intrauterine device removal is not considered a concomitant procedure.
* Subjects with any general health condition or systemic disease that may represent, in the opinion of the physician, a potential increased risk associated with device use or pregnancy
* Subjects with a close affiliation with the investigational site, e.g. closely related or affiliated with the investigator (such as dependent, employee or student of the investigational site, or sponsor's staff)
Minimum Eligible Age

21 Years

Maximum Eligible Age

44 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Glendale, Arizona, United States

Site Status

Phoenix, Arizona, United States

Site Status

Colorado Springs, Colorado, United States

Site Status

Augusta, Georgia, United States

Site Status

Fort Wayne, Indiana, United States

Site Status

Newburgh, Indiana, United States

Site Status

Grand Blanc, Michigan, United States

Site Status

Saginaw, Michigan, United States

Site Status

Wayne State University Physicians Group

Southfield, Michigan, United States

Site Status

Mayo Clinic - Rochester

Rochester, Minnesota, United States

Site Status

Winston-Salem, North Carolina, United States

Site Status

Dayton, Ohio, United States

Site Status

Tennessee Women's Care, PC

Nashville, Tennessee, United States

Site Status

Vanderbilt University Medical Center

Nashville, Tennessee, United States

Site Status

Fort Worth, Texas, United States

Site Status

Houston, Texas, United States

Site Status

Countries

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United States

Related Links

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https://clinicaltrials.bayer.com/

Click here to find results for studies related to Bayer Healthcare products.

Other Identifiers

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17069

Identifier Type: -

Identifier Source: org_study_id

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