Study Results
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View full resultsBasic Information
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COMPLETED
PHASE2
131 participants
INTERVENTIONAL
2012-01-31
2014-04-30
Brief Summary
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The investigators' hypothesis is that minocycline will reduce post-operative pain.
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Detailed Description
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The investigators will perform a futility analysis to assess if a larger trial would be a reasonable next step after this pilot study.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
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minocycline
perioperative minocycline for 5 days, starting 2 hours prior to surgery then 100mg BID
Minocycline
RCT blinded placebo trial
Placebo
PLacebo
placebo
RCT blinded placebo trial
Interventions
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Minocycline
RCT blinded placebo trial
placebo
RCT blinded placebo trial
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
ALL
Yes
Sponsors
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Stanford University
OTHER
VA Palo Alto Health Care System
FED
Responsible Party
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Catherine Curtin
Staff Physician
Principal Investigators
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Catherine Curtin, MD
Role: PRINCIPAL_INVESTIGATOR
Palo Alto Veterans Hsopital
Locations
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Palo Alto VA
Palo Alto, California, United States
Countries
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Other Identifiers
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RX000487
Identifier Type: -
Identifier Source: org_study_id
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