Calcium Ionophore Solution Can Increase Fertilization Rate in Patients During Intracytoplasmic Sperm Injection(ICSI) Who Have Poor Ovarian Reserve?
NCT ID: NCT02045914
Last Updated: 2014-01-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
162 participants
INTERVENTIONAL
2014-01-31
2014-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
NONE
Study Groups
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control group
the patients who have no intervention with calcium ionophore during ICSI cycle
No interventions assigned to this group
calcium ionophore
the patients whose oocytes are incubated with calcium ionophore solution during ICSI cycle
calcium ionophore solution
After microinjection of sperm into the oocyte, oocytes are incubated for 15 minutes in a 30 microlitre droplet of calcium ionomycin solution
Interventions
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calcium ionophore solution
After microinjection of sperm into the oocyte, oocytes are incubated for 15 minutes in a 30 microlitre droplet of calcium ionomycin solution
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* infertile females who are poor ovarian reserve
Exclusion Criteria
* infertile female who have endometriosis
23 Years
39 Years
FEMALE
No
Sponsors
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Baskent University
OTHER
Responsible Party
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Pinar Caglar Aytac
Effect of calcium ionophore solution on fertilization rate during ICSI cycles of poor ovarian reserve patients
Principal Investigators
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esra bulgan kilicdag, prof md
Role: STUDY_DIRECTOR
Baskent University
Huriye Ayse Parlakgumus, md
Role: STUDY_CHAIR
Baskent University
Pinar Caglar Aytac, md
Role: PRINCIPAL_INVESTIGATOR
Baskent University
Cok Tayfun, md
Role: STUDY_CHAIR
Baskent University
Bulent Haydardedeoglu, assoc Prof
Role: STUDY_CHAIR
Baskent University
Erhan Simsek, md
Role: STUDY_CHAIR
Baskent University
Locations
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baskent university obstetric and gynecology, reproductive endocrinology and IVF unit
Adana, Kisla, Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Role: primary
References
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Caglar Aytac P, Kilicdag EB, Haydardedeoglu B, Simsek E, Cok T, Parlakgumus HA. Can calcium ionophore "use" in patients with diminished ovarian reserve increase fertilization and pregnancy rates? A randomized, controlled study. Fertil Steril. 2015 Nov;104(5):1168-74. doi: 10.1016/j.fertnstert.2015.07.1163. Epub 2015 Sep 3.
Other Identifiers
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KA1-191
Identifier Type: -
Identifier Source: org_study_id
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