Study of SPARC1103 in Subjects With Spasticity

NCT ID: NCT02027025

Last Updated: 2019-05-03

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

142 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-04-21

Study Completion Date

2017-04-28

Brief Summary

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Study of SPARC1103 in subjects with spasticity

Detailed Description

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Conditions

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Spasticity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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SPARC 1103 low dose

The subjects will receive SPARC 1103 low dose

Group Type ACTIVE_COMPARATOR

SPARC1103 low dose

Intervention Type DRUG

once daily

SPARC1103 high dose

The subjects will receive SPARC1103 high dose

Group Type ACTIVE_COMPARATOR

SPARC1103 high dose

Intervention Type DRUG

once daily

SPARC Placebo

The subjects will receive SPARC Placebo

Group Type PLACEBO_COMPARATOR

SPARC Placebo

Intervention Type DRUG

Interventions

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SPARC1103 low dose

once daily

Intervention Type DRUG

SPARC1103 high dose

once daily

Intervention Type DRUG

SPARC Placebo

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Men and women greater than or equal to 18 years of age
* Willing to sign the informed consent form
* Women of child bearing potential willing to practice an acceptable method of birth control
* Known history of spasticity due to MS

Exclusion Criteria

* Administration of an investigational drug or device within 30 days prior to Screening Visit 1
* Unable to comply with trial procedures in the opinion of the Investigator
* Concomitant neurologic conditions causing spasticity
* Any medical condition, including psychiatric disease or epilepsy, which would interfere with the interpretation of the trial results
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sun Pharma Advanced Research Company Limited

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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SPARC Site 4

Long Beach, California, United States

Site Status

SPARC Site 6

San Diego, California, United States

Site Status

SPARC Site 10

Aurora, Colorado, United States

Site Status

SPARC Site 2

Jacksonville, Florida, United States

Site Status

SPARC Site 15

Miami, Florida, United States

Site Status

SPARC Site 7

Miami Springs, Florida, United States

Site Status

SPARC Site 5

Orlando, Florida, United States

Site Status

SPARC Site 13

Tampa, Florida, United States

Site Status

SPARC Site 11

Kansas City, Kansas, United States

Site Status

SPARC Site 3

Lenexa, Kansas, United States

Site Status

SPARC Site 1

Bingham Farms, Michigan, United States

Site Status

SPARC Site 14

Albuquerque, New Mexico, United States

Site Status

SPARC Site 9

Charlotte, North Carolina, United States

Site Status

SPARC Site 8

Cleveland, Ohio, United States

Site Status

SPARC Site 12

Richland, Washington, United States

Site Status

SPARC Site 18

Moscow, , Russia

Site Status

SPARC Site 17

Nizhny Novgorod, , Russia

Site Status

SPARC Site 20

Samara, , Russia

Site Status

SPARC Site 19

Smolensk, , Russia

Site Status

SPARC Site 16

Ufa, , Russia

Site Status

SPARC Site 22

Dnipro, , Ukraine

Site Status

SPARC Site 21

Ivano-Frankivsk, , Ukraine

Site Status

SPARC Site 23

Lviv, , Ukraine

Site Status

Countries

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United States Russia Ukraine

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CLR_11_03

Identifier Type: -

Identifier Source: org_study_id

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